Results 71 to 80 of about 1,632,251 (310)
Yantu gongcheng xuebaoThe theory of thermal consolidation is widely applied in engineering projects such as ground source heat pumps, energy piles, and heating pipelines, which involve thermo-hydro-mechanical coupling in geomaterials. The physical and mechanical properties of
HAN Tao 1, 2, LI Kuo 2, LU Mengmeng 1, 2
doaj +1 more source
Crystals, 2023 Bulk nanostructured metals and alloys are finding increasing structural applications due to their superior mechanical properties. The methods that rely on the severe plastic deformation technique for effecting microstructural refinement through imposing ...
Muralimohan Gurusamy, Balkrishna C. Rao
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Strain-tunable synthetic gauge fields in topological photonic graphene
, 2021 We propose a straightforward and effective approach to design, by strain-engineering, photonic topological insulators supporting high quality factors edge states.
Claudio Conti (250294) +6 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Investigation of advanced strain-path dependent material models for sheet metal forming simulations [PDF]
, 2006 Sheet metal forming processes often involve complex loading sequences. To improve the prediction of some undesirable phenomena, such as springback, physical behavior models should be considered.
BALAN, Tudor +5 more
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Job strain and cardiovascular disease risk factors: meta-analysis of individual-participant data from 47,000 men and women [PDF]
, 2013 Job strain is associated with an increased coronary heart disease risk, but few large-scale studies have examined the relationship of this psychosocial characteristic with the biological risk factors that potentially mediate the job strain - heart ...
Westerlund, Hugo, +212 more
core +1 more source