Results 91 to 100 of about 1,632,251 (310)

Modelling of behaviour of metals at high strain rates [PDF]

, 2006
The aim of the work presented in this thesis was to produce the improvement of the existing simulation tools used for the analysis of materials and structures, which are dynamically loaded and subjected to the different levels of temperatures and strain ...
Panov, Vili
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

On large deformations of thin elasto-plastic shells: Implementation of a finite rotation model for quadrilateral shell element [PDF]

, 1997
A large-deformation model for thin shells composed of elasto-plastic material is presented in this work, Formulation of the shell model, equivalent to the two-dimensional Cosserat continuum, is developed from the three-dimensional continuum by employing ...
Brank, Boštjan, Perić, Djordje, Damjanić, Frano B   +2 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Texture Evolution of AZ31 Magnesium Alloy Sheet at High Strain Rates

, 2010
In the current contribution the mechanical behaviour at high strain rates of AZ31 magnesium alloy sheet is studied. Uniaxial deformation properties were studied by means of tensile split Hopkinson pressure bar (SHPB) at different temperatures.
Hurtado, I., Letzig, D., Gálvez, F., Yi, S., Pérez-Prado, M. T., Dudamell, N. V., Pérez Prado, María Teresa, Dudamell, N.V., Ulacia, I., Gálvez Díaz-Rubio, Francisco   +9 more
core   +2 more sources

Beta-type Ti-Nb-Zr-Cr alloys with large plasticity and significant strain hardening

Materials & Design, 2019
A series of Ti-25Nb-8Zr-xCr (x = 0, 2, 4, 6, 8 wt%) alloys were designed based on DV-Xα cluster method and e/a¯-Δr¯ diagram with an anticipation to obtain high plasticity and significant strain hardening.
S.F. Jawed, C.D. Rabadia, Y.J. Liu, L.Q. Wang, Y.H. Li, X.H. Zhang, L.C. Zhang   +6 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Shear viscosity and nonlinear behaviour of whole blood under large amplitude oscillatory shear [PDF]

, 2013
We investigated experimentally the rheological behavior of whole human blood subjected to large amplitude oscillatory shear under strain control to assess its nonlinear viscoelastic response.
Sousa, P.C., Mónica Oliveira, Fernando Tavares de Pinho, Oliveira, Monica, Alves, M.A., R. Vaz, P. C. Sousa, Carneiro, J., Vaz, R., Pinho, F.T., J. Carneiro, A. Cerejo, Cerejo, A., Manuel Alves   +13 more
core   +1 more source

Energetic Approach to Large Strain Gradient Crystal Plasticity

Acta Polytechnica, 2012
We formulate a problem of the evolution of elasto-plastic materials subjected to external loads in the framework of large deformations and multiplicative plasticity.
Jan Kratochvíl, Martin Kružík
doaj