Results 131 to 140 of about 15,790,105 (302)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The role of energy shear in the collapse of protohaloes

open access: yesAstronomy & Astrophysics
Dark matter haloes form from the collapse of matter around special positions in the initial field, those where the local matter flows converge to a point. For such a triaxial collapse to take place, the energy shear tensor (the source of the evolution of
Musso Marcello, Sheth Ravi K.
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Radio-loudness Statistics of Quasars from Quaia-VLASS

open access: yesThe Astrophysical Journal Supplement Series
Quasars are objects of high interest in extragalactic astrophysics, cosmology, and astrometry. One of their useful qualities is their potential radio-loudness.
Nestor Arsenov   +3 more
doaj   +1 more source

Galaxy transformation across the cosmic web: The influence zone of filaments

open access: yesAstronomy & Astrophysics
Context. The matter distribution in the Universe exhibits a rich variety of structures, and they form the so-called cosmic web. These structures arise from the anisotropic gravitational collapse of primordial density fluctuations and define the pathways ...
Alfonso L. Aguerri J., Zarattini Stefano
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Taxation and economic development in Ohio : a blueprint for the future : final report of the Commission to Study the Ohio Economy and Tax Structure.

open access: yes, 1994
"December 23, 1994."; Includes bibliographical references (p.
Commission to Study the Ohio Economy and Tax Structure.
core  

Euclid preparation

open access: yesAstronomy & Astrophysics
We investigated the accuracy and range of validity of the perturbative model for the two-point (2PCF) and three-point (3PCF) correlation functions in real space in view of the forthcoming analysis of the Euclid mission spectroscopic sample.
Guidi M.   +309 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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