Results 241 to 250 of about 15,790,105 (302)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Automated Surface-Based Segmentation of Deep Gray Matter Regions Based on Diffusion Tensor Images Reveals Unique Age Trajectories Over the Healthy Lifespan. [PDF]

NMR Biomed
Little G, Acosta-Franco JA, Beaulieu C.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Biotic interactions biogeography: A framework for understanding how species interactions shape biodiversity patterns across scales. [PDF]

PLoS Biol
Galiana N, Araújo MB.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Integration of Morphology, Histology, and Ultrastructure of the Gall-Inducing <i>Andricus quercustozae</i> (Cynipidae) Larval Alimentary Canal. [PDF]

Insects
Puljas S, Bočina I, Kević N, Šamanić I, Kamenjarin J, Ćurlin P.   +5 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Objective quality assessment for precision functional MRI data. [PDF]

Neuron
Lynch CJ, Chang M, Elbau I, Gordon EM, Laumann TO, Du J, Ladwig Z, Lueckel M, Perez DC, Summerville I, Chou J, Johnson M, Ho C, Manfredi N, Nilchian P, Solomonov N, Goldwaser E, Ng T, Moia S, Caballero-Gaudes C, Downar J, Vila-Rodriguez F, Gregory E, Daskalakis ZJ, Blumberger DM, Kay K, Buchanan DM, Williams N, Bhati MT, Clauss J, Zebley B, Victoria LW, Power JD, Grosenick L, Gunning FM, Liston C.   +35 more
europepmc   +1 more source

Trifunctional synergistically designed 3D-Printed bone scaffold for infectious bone defect therapy: design strategy and clinical translation outlook. [PDF]

Front Bioeng Biotechnol
Zhao P, Qiao Z.
europepmc   +1 more source

0N4R Tau aggregates producing morphologically different and structurally similar "on-path" and "off-path" oligomers.

Chem Commun (Camb)
Skrehot JT, Matveyenka M, Kurouski D.
europepmc   +1 more source