Results 51 to 60 of about 7,634,652 (259)

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Double Trouble in Patients With Large Core Ischemic Stroke:Intracranial Thrombo-Embolic Occlusion and Extracranial Carotid Occlusion [PDF]

Approximately 15%–20% of the patients with acute ischemic stroke caused by an intracranial large vessel occlusion have evidence of extracranial atherosclerotic disease in the ipsilateral carotid artery.
Dippel, Diederik W.J., Uyttenboogaart, Maarten; id_orcid   +1 more
core   +1 more source

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

Advanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching, Hinako Ichikawa, Aya Motoyoshi, Shin Tanaka, Liam Morrow, Satoshi Shirae, Noriko Sakai, Shohei Kitahata, Michiko Mandai, Kazuaki Kadonosono   +9 more
wiley   +1 more source

Use of Diffusion‐Weighted Imaging‐Alberta Stroke Program Early Computed Tomography Score (DWI‐ASPECTS) and Ischemic Core Volume to Determine the Malignant Profile in Acute Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Malignant profiles were identified by imaging profiles and unfavorable outcomes that have poor response to reperfusion therapy. Many trials have used this profile in their inclusion criteria including large‐vessel occlusion acute ischemic ...
Takeshi Yoshimoto, Manabu Inoue, Hiroshi Yamagami, Kyohei Fujita, Kanta Tanaka, Daisuke Ando, Kazutaka Sonoda, Naruhiko Kamogawa, Masatoshi Koga, Masafumi Ihara, Kazunori Toyoda   +10 more
doaj   +1 more source

Preliminary experience with recanalization of large vessel occlusion due to underlying long-segment dissection using a standby microwire technique

Frontiers in Neurology, 2022
PurposeThis study aimed at investigating a novel standby microwire technique to facilitate revascularization of large vessel occlusion due to underlying long-segment dissection.MethodsPatients with acute ischemic stroke with emergent large vessel ...
Xiaoxi Zhang, Hongye Xu, Zhengzhe Feng, Weilong Hua, Hongjian Shen, Lei Zhang, Yongxin Zhang, Pengfei Xing, Pengfei Yang, Xiaolong Xu, Zifu Li   +10 more
doaj   +1 more source

TacScope: A Miniaturized Vision‐Based Tactile Sensor for Surgical Applications

Advanced Robotics Research, EarlyView.
TacScope is a compact, vision‐based tactile sensor designed for robot‐assisted surgery. By leveraging a curved elastomer surface with pressure‐sensitive particle redistribution, it captures high‐resolution 3D tactile feedback. TacScope enables accurate tumor detection and shape classification beneath soft tissue phantoms, offering a scalable, low‐cost ...
Md Rakibul Islam Prince, Sheeraz Athar, Pokuang Zhou, Yu She   +3 more
wiley   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Head Down Position Before Endovascular Treatment for Large Vessel Occlusion: Clinical Trial Design

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Head down position (HDP) shows potential benefits in acute ischemic stroke. Although −20° HDP appears safe, feasible, and potentially beneficial in patients with large artery atherosclerosis without reperfusion therapy, its value before ...
Zhao‐Xia Fei, Ying‐Jie Dai, Xin‐Hong Wang, Hui‐Sheng Chen   +3 more
doaj   +1 more source

What predicts large vessel occlusion in mild stroke patients?

BMC Neurology, 2023
Background and purpose Mild acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) may benefit from thrombolysis or thrombectomy therapy. However, the predictors for LVO in mild AIS patients have not been extensively explored. We aimed to
Zhengzhao Lu, Yunyun Xiong, Kaixuan Yang, Hongqiu Gu, Chunmiao Duan, Xingquan Zhao, Xia Meng, Yongjun Wang   +7 more
doaj   +1 more source

External Validation of Atherosclerotic Neuroimaging Biomarkers in Emergent Large‐Vessel Occlusion

, 2023
Background Intracranial atherosclerosis related large vessel occlusion (ICAS‐LVO) is the major cause of failed mechanical thrombectomy. ICAS‐LVO causes reocclusion or a fixed focal stenosis, leading to suboptimal revascularization and poor functional ...
Mudassir Farooqui, Barnes, Andrew V., Jeffrey J. Fletcher, Elias, Augusto E., Aditya S. Pandey, Sudeepta Dandapat, Siddiqui, Fazeel M., PA\u2010C, Alexis Carroll, Santiago Ortega‐Gutierrez, Aaron Rodriguez‐Calienes, Ume, Kiddy L., Rodriguez\u2010Calienes, Aaron, Fazeel M. Siddiqui, Dandapat, Sudeepta, Henry, Alayna N., Pandey, Aditya S., Ortega\u2010Gutierrez, Santiago, Alayna N. Henry, Rajah, Gary, Alexis Carroll PA‐C, Gary Rajah, Kiddy L. Ume, Andrew V. Barnes, Farooqui, Mudassir, Augusto E. Elias, Fletcher, Jeffrey J.   +25 more
core   +1 more source