Results 71 to 80 of about 7,488,458 (210)

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Idiopathic Pulmonary Hemosiderosis in a Young Adult Patient: A Rare Case

The Journal of Association of Chest Physicians, 2018
Idiopathic pulmonary hemosiderosis (IPH) is often an ignored and rare cause of diffuse alveolar hemorrhage (DAH). It is characterized by triad of hemoptysis, anemia, and alveolar opacity on radiology.
Abhishek Agarwal, Rahul Kumar, Anand Jaiswal, Vikram Vohra, Poulomi Chatterjee   +4 more
doaj   +1 more source

Identification of Copy Number Variants as a Suspected Cause of Cerebral Small Vessel Disease

Clinical Genetics, EarlyView.
Whole‐exome sequencing of 111 patients with suspected familial cerebral small vessel disease (CSVD) identified novel copy number variants in four patients across NOTCH3, LMNB1, and COL4A2, using bioinformatic and molecular techniques. These validated CNVs suggest structural variation is an underrecognized potential causal contributor to monogenic CSVD ...
Solomon K. Guyler, Neven Maksemous, Rodney A. Lea, Robert A. Smith, Heidi G. Sutherland, Lyn R. Griffiths   +5 more
wiley   +1 more source

Annular leukocytoclastic vasculitis associated with isolated anti-β2 glycoprotein I immunoglobulin G positivity: A case report

SAGE Open Medical Case Reports
Vasculitis comprises a spectrum of disorders defined inflammation of the blood vessel walls and is categorized based on vessel size into small-, medium-, and large-vessel vasculitis. The histological characteristics of leukocytoclastic vasculitis include
Saleha Abdulrahman Aldawsari, Ajlan Hashim Alajlani, Abdulelah Nabil Alkadi, Sadeq Wasil Al-Dandan   +3 more
doaj   +1 more source

ACR Appropriateness Criteria® Noncerebral Vasculitis

, 2021
Noncerebral vasculitis is a wide-range noninfectious inflammatory disorder affecting the vessels. Vasculitides have been categorized based on the vessel size, such as large-vessel vasculitis, medium-vessel vasculitis, and small-vessel vasculitis. In this
Azene, Ezana M., Kalva, Sanjeeva P., Pelaez Freidel, Andres, Ledbetter, Luke N., El Khouli, Riham H., Hedgire, Sandeep S., Mauro, David M., Pelaez, Andres, Williamson, Eric E., Chareonthaitawee, Panithaya, Burns, Judah, Dill, Karin E., Expert Panel on Vascular Imaging, Steigner, Michael L., Pillai, Anil K., Verma, Nupur, Desjardins, Benoit, Singh, Nimarta, Lee, Yoo Jin, Suranyi, Pal S., Aghayev, Ayaz, Grayson, Peter C., Eric E. Williamson, Sanjeeva P. Kalva, Ezana M. Azene, Nimarta Singh, Sandeep S. Hedgire, Ayaz Aghayev, Yoo Jin Lee, Nupur Verma, Andres Pelaez, Anil K. Pillai, Peter C. Grayson, Michael L. Steigner, David M. Mauro, Judah Burns, Benoit Desjardins, Pal S. Suranyi, Luke N. Ledbetter, Karin E. Dill, Riham H. El Khouli, Panithaya Chareonthaitawee   +41 more
core   +1 more source

Multi-Modality Imaging in Vasculitis

Diagnostics
Systemic vasculitides are a rare and complex group of diseases that can affect multiple organ systems. Clinically, presentation may be vague and non-specific and as such, diagnosis and subsequent management are challenging.
Mohamed N. Allam, Nima Baba Ali, Ahmed K. Mahmoud, Isabel G. Scalia, Juan M. Farina, Mohammed Tiseer Abbas, Milagros Pereyra, Moaz A. Kamel, Kamal A. Awad, Yuxiang Wang, Timothy Barry, Steve S. Huang, Ba D. Nguyen, Ming Yang, Clinton E. Jokerst, Felipe Martinez, Chadi Ayoub, Reza Arsanjani   +17 more
doaj   +1 more source

Drug-induced vasculitis

Indian Journal of Rheumatology, 2019
Vascular injury due to drugs is recognized as a distinct entity under the Chapel Hill Consensus Conference 2012 definitions for vasculitis. Drug-induced vasculitis (DIV) may affect various types of vessels.
Durga Prasanna Misra, Pallavi Patro, Aman Sharma   +2 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Large- and medium-sized vessel systemic vasculitis with testicular involvement

Vasculitis of the large vessels (aorta and its major branches) frequently also affects small- and medium-sized arteries. Testicular and spermatic vessel lesions have been described in giant cell arteritis and Takayasu’s arteritis.
González-Peramato Gutiérrez, María del Pilar, Nistal Martín Serrano, Manuel   +1 more
core   +1 more source