Results 141 to 150 of about 3,629,719 (185)

Insulin-like growth factor receptor signaling in physiology and disease. [PDF]

Signal Transduct Target Ther
Dilawar M, Malik A, Liao J, Shen P, Huang Z, Zhang P, Wang J, Zhang N, Nisar MF, Chen G.   +9 more
europepmc   +1 more source

Advancing HIV pre-exposure prophylaxis (PrEP) implementation in Canada: a scoping review protocol of programmes, practices and policies. [PDF]

BMJ Open
Chakraborty D, Djiadeu P, Ziegler C, Chabikuli A, Ifeanacho E, Awoliyi M, Zuta H, Djuidje De Pandja G, Ajiboye O, Ajiboye O, Nelson LE, Rourke SB, Ajiboye W.   +12 more
europepmc   +1 more source

Near-Adult Height Outcomes in Patients Treated With rhIGF-1 for Severe Growth Failure: Real-World IGFD Registry Data.

J Clin Endocrinol Metab
Ramon-Krauel M, Polak M, Maghnie M, Woelfle J, Sert C, Perrot V, Bang P.   +6 more
europepmc   +1 more source

Growth Hormone and Brain Regeneration: Evidence from Clinical Studies in Dementia, Traumatic Brain Injury, and Stroke: A Systematic Review. [PDF]

Int J Mol Sci
Bianchi VE, Visbal LC, Devesa J.
europepmc   +1 more source

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Laron syndrome – A historical perspective

Reviews in Endocrine and Metabolic Disorders, 2020
Laron Syndrome (LS) [OMIm#262500], or primary GH insensitivity, was first described in 1966 in consanguineous Jewish families from Yemen. LS is characterized by a typical phenotype that includes dwarfism, obesity and hypogenitalism. The disease is caused by deletions or mutations of the GH-receptor gene, causing high serum GH and low IGF-I serum levels.
Zvi, Laron, Haim, Werner
openaire   +3 more sources

Adult patients with Laron syndrome tend to develop the metabolic syndrome

Growth Hormone and IGF Research
BACKGROUND The metabolic Syndrome is the name of a cluster of abnormal clinical and metabolic states, which constitute a risk factor for diabetes and cardiovascular disease.
Zvi Laron, Rivka Kauli
exaly   +2 more sources

Anaesthetic management of a parturient with Laron syndrome

International Journal of Obstetric Anesthesia, 2011
We report a case of a parturient with Laron syndrome, a rare form of dwarfism which results from an inability to generate insulin-like growth factor 1. In addition to dwarfism these patients may have craniofacial abnormalities, atlantoaxial instability, spinal stenosis and metabolic, musculoskeletal and genitourinary abnormalities.
Kailash Bhatia
exaly   +3 more sources

Diabetes mellitus with Laron syndrome: case report

Journal of Pediatric Endocrinology and Metabolism, 2013
There are different opinions concerning changes in glucose metabolism in patients with Laron syndrome. In this paper we discuss the treatment results of our patient with Laron syndrome who developed diabetes during late adolescence. A 19-year-old boy with Laron syndrome was referred to our clinic for follow-up. He had been diagnosed with Laron syndrome
Havva Nur Peltek Kendirci, Şenay Savaş-Erdeve, Semra Çetinkaya   +2 more
exaly   +3 more sources