Results 1 to 10 of about 2,676,116 (139)

Bovine Somatotropin Alters Myosin Heavy Chains and Beta Receptors in Skeletal Muscle of Feedlot Heifers with Little Impact on Live or Carcass Performance

Meat and Muscle Biology, 2021
The objective was to determine whether recombinant bovine somatotropin (rbST) enhanced live performance,skeletal muscle biological activity, and beta-adrenergic receptor expression of feedlot heifers during the finishing phase.
Alex Thompson, Bradley Johnson, Gary Vogel, Jerilyn Hergenreder, Jessica Baggerman, Kari Spivey, Rand Broadway, Tyler Harris, Zachary Smith   +8 more
doaj   +4 more sources

Characterization of human somatotropin binding to detergent-solubilized lactogenic receptors from rat liver. [PDF]

Biochemical Journal, 1981
Lactogenic receptors from rat liver microsomal fraction (‘microsomes’) were extracted by treatment with 1% (w/v) Triton X-100. Triton X-100 exerts an inhibitory effect on both the binding reaction and the separation of the free hormone from the complex.
Juan S. Bonifacino, S. Sánchez, Alejandro C. Paladini   +2 more
semanticscholar   +3 more sources

Neither bovine somatotropin nor growth hormone-releasing factor alters expression of thyroid hormone receptors in liver and mammary tissues. [PDF]

Journal of Dairy Science, 2011
Physiological effects of thyroid hormones are mediated primarily by binding of triiodothyronine to specific nuclear receptors. Organ-specific changes in production of triiodothyronine from its prohormone, thyroxine, have been hypothesized to target the action of thyroid hormones on the mammary gland and play a role in mediating or augmenting a ...
Anthony V. Capuco, M. Binelli, H. Tucker
semanticscholar   +3 more sources

Structures of the somatotropin receptor and prolactin receptor on rat hepatocytes characterized by affinity labelling. [PDF]

Biochemical Journal, 1984
Human somatotropin competed for 125I-human somatotropin binding to hepatocytes from female or male rats. Bovine somatotropin and prolactin each inhibited part, but not all, of the uptake of 125I-human somatotropin. The binding of 125I-prolactin was inhibited by human somatotropin and prolactin, but not by bovine somatotropin.
Kazuyo Yamada, David B. Donner
semanticscholar   +3 more sources

Fluorescence-Based Study of Oligonucleotide Interactions With Recombinant Proteins: Insulin, Interferon α2-β, Somatotropin, and Their Receptors

Innovative Biosystems and Bioengineering
Background. Oligonucleotides (OLNs) can participate in a wide range of protein-ligand interactions and perform numerous cellular functions by forming structures that enable specific interactions with DNA, RNA, and proteins, what is crucial for many ...
O. Nuzhnyi, R. Nikolaiev, Z. Tkachuk
semanticscholar   +5 more sources

Binding in vitro to rat liver receptors does not correlate with activities in vivo of bovine somatotropin. Use of chemically modified derivatives as probes. [PDF]

Biochemical Journal, 1984
Bovine somatotropin with an increasing number of its carboxylate groups modified by reaction with glycine methyl ester in the presence of a water-soluble carbodi-imide was tested for its activity in different bioassays. Only those derivatives which were known to be active in the body-weight-increase bioassay were able to compete with 125I-labelled ...
Leonor P. Roguin, J. Delfino, Natalio Vita, Alejandro C. Paladini   +3 more
semanticscholar   +3 more sources

A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential.

Journal of Medicinal Chemistry, 2003
A rational drug design approach, capitalizing on structure-activity relationships and involving transposition of functional groups from somatotropin release inhibitory factor (SRIF) into a reduced size cyclohexapeptide template, has led to the discovery of SOM230 (25), a novel, stable cyclohexapeptide somatostatin mimic that exhibits unique high ...
I. Lewis, W. Bauer, R. Albert, N. Chandramouli, J. Pless, G. Weckbecker, C. Bruns   +6 more
semanticscholar   +3 more sources

Effect of bovine somatotropin and food deprivation on beta-adrenergic and A1 adenosine receptor binding in adipose tissue of lactating cows.

Domestic Animal Endocrinology, 1995
Lactating Holstein cows were used to assess the effect of bovine somatotropin (bST; n = 8) and fasting (FAST; n = 4) on ligand binding to beta-adrenergic (BAR) and Type-1 adenosine (A1R) receptors in adipose tissue.
K. Houseknecht, D. E. Bauman, G. Carey, H. J. Mersmann   +3 more
semanticscholar   +3 more sources

Significant down-regulation of growth hormone receptor expression revealed as a new unfavorable prognos- tic factor in hepatitis C virus-related hepatocellular carcinoma [PDF]

Clinical and Molecular Hepatology, 2021
Background/Aims Growth hormone (GH) is the main regulator of somatic growth, metabolism, and gender dimorphism in the liver. GH receptor (GHR) signaling in cancer is derived from a large body of evidence, although the GHR signaling pathway involved in ...
Ching-Chih Lin, Ta-Wei Liu, Ming-Lun Yeh, Yi-Shan Tsai, Pei-Chien Tsai, Chung-Feng Huang, Jee-Fu Huang, Wan-Long Chuang, Chia-Yen Dai, Ming-Lung Yu   +9 more
doaj   +1 more source

Somatostatin and Its Receptor System in Colorectal Cancer

Biomedicines, 2021
Somatostatin (SST)/somatotropin release-inhibiting factor (SRIF) is a well-known neuropeptide, widely distributed in the central and peripheral nervous systems, that regulates the endocrine system and affects neurotransmission via interaction with five ...
Aldona Kasprzak
doaj   +1 more source