Results 21 to 30 of about 3,213,203 (202)

SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile [PDF]

European Journal of Endocrinology, 2002
OBJECTIVE: The aim of the present study was to identify a small, metabolically stable somatotropin release inhibiting factor (SRIF) analog with a more universal binding profile similar to that of natural somatostatin, resulting in improved pharmacological properties and hence new therapeutic uses. DESIGN: A rational drug design approach was followed by
C, Bruns, I, Lewis, U, Briner, G, Meno-Tetang, G, Weckbecker   +4 more
openaire   +2 more sources

Covalent cross-linking of the bovine somatotropin dimer. Effects on growth-promoting, receptor-binding and immunological activities and preliminary characterization of the self-association [PDF]

Biochemical Journal, 1983
Bovine somatotropin, at pH 8.5 in 0.02 M-Bicine [NN-bis-(2-hydroxyethyl)glycine]/0.09M-NaCl, showed by frontal analysis the characteristics of a rapid monomer-dimer equilibrium whose dissociation constant was estimated to be 6.6×10(-6)M. Reaction of the hormone with dimethyl suberimidate lead to covalent cross-linking of the dimeric species.
H N, Fernández, J M, Delfino
openaire   +2 more sources

Single strand conformation polymorphism (SSCP) detection in six genes in Portuguese indigenous sheep breed [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2001
Evaluation of the genetic diversity for six genes in forty animals of the Portuguese indigenous sheep breed (Ovis aries) ""Churra da Terra Quente"" was done.
Guedes-Pinto H., Bastos E., Cravador A., Azevedo J.   +3 more
doaj  

Exploring the growth hormone and growth hormone receptor gene families in rainbow trout (Oncorhynchus mykiss): A genome-wide perspective

In Silico Research in Biomedicine
The growth hormone (GH) and growth hormone receptor (GHR) system is a central regulator of growth and metabolism in vertebrates, with critical implications for aquaculture productivity and functional genomics research.
Neethi Ajith, Urwah Farooq, Tabinda Waheed, Suvadip Ghara, Somasundaram Iyyappan, Irfan Ahmad Bhat, Irfan Ahmad Khan, Mohd Ashraf Rather   +7 more
doaj   +1 more source

Somatostatin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

IUPHAR/BPS Guide to Pharmacology CITE, 2019
Somatostatin (somatotropin release inhibiting factor) is an abundant neuropeptide, which acts on five subtypes of somatostatin receptor (SST1-SST5; nomenclature as agreed by the NC-IUPHAR Subcommittee on Somatostatin Receptors [89]).
Corinne Bosquet, J. Castaño, Z. Csaba, M. Culler, P. Dournaud, J. Epelbaum, W. Feniuk, A. Harmar, R. Hills, L. Hofland, D. Hoyer, P. Humphrey, H. Kreienkamp, A. Lupp, S. Melmed, W. Meyerhof, A. O'Carroll, Y. Patel, T. Reisine, J. Reubi, M. Schindler, H. Schmid, A. Schonbrunn, S. Schulz, John E. Taylor, G. Tulipano, A. Vezzani, H. Wester   +27 more
semanticscholar   +1 more source

Actions of NPY, and Its Y1 and Y2 Receptors on Pulsatile Growth Hormone Secretion during the Fed and Fasted State

Journal of Neuroscience, 2014
The hypothalamic NPY system plays an important role in regulating food intake and energy expenditure. Different biological actions of NPY are assigned to NPY receptor subtypes.
Lili Huang, H. Y. Tan, M. Fogarty, Z. Andrews, J. Veldhuis, H. Herzog, F. Steyn, Cheng Chen   +7 more
semanticscholar   +1 more source

Space‐Time Metasurface Antenna Enabled High‐Dimensional Electromagnetic Modulation for Intrinsic Physical Layer Security

Advanced Science, EarlyView.
The concept of high‐dimensional EM modulation using the STMA for physical layer secure communication is illustrated in figure. The STMA consists of a series of programmable unit cells, with 1‐bit reconfigurable phase states (0/π). The STMA is excited by a monochromatic continuous wave (CW) at frequency fc and controlled by a field‐programmable gate ...
Xinyu Fang, Yiqing Sun, Chenfeng Yang, Siran Wang, Zheng Xing Wang, Kaixu Wang, Geng‐Bo Wu   +6 more
wiley   +1 more source

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

NbN Broadband Plasmonic Absorbers for Efficient Hot‐Carrier Injection Toward Improved Solar‐to‐Hydrogen Conversion

Advanced Science, EarlyView.
Niobium nitride (NbN) broadband plasmonic metasurface absorbers provide an efficient platform for solar‐energy conversion through hot‐carrier injection. Quasi‐epitaxial NbN features a low work function of 4.0 eV, reducing the interfacial injection barrier and facilitating charge transfer into adjacent photocatalysts.
Tzu‐Yu Peng, Tse‐Fu Huang, Takeshi Yamaguchi, Jia‐Wern Chen, Hsing‐Yu Kuo, Ying‐Rang Zhuang, Hung Wei Shiu, Seongmin Im, Yang Zhao, Takuo Tanaka, Ho‐Hsiu Chou, Yu‐Jung Lu   +11 more
wiley   +1 more source

Effect of Recombinant Bovine Somatotropin on Libido, Pre and Post Freezing Semen Parameters in Cholistani Bulls -

, 2016
Growth hormone (GH) is secreted by the anterior pituitary gland and presence of growth hormone receptors has been reported in the mammalian reproductive tract.
Shuja Hakim, M. Zubair, Maqbool Ahmad, Shafia Tahseen Gull, Ali Faisal Murtaza, S. Umar   +5 more
semanticscholar   +1 more source