Results 91 to 100 of about 118,785 (268)

Significance of tumor height, size, and Total Mesorectal Excision (TME) in the discrepancy between POLARS and actual LARS score in rectal tumors post Low Anterior Resection (LAR)

Bali Medical Journal
Background: The number of cases of rectal tumors is increasing. Currently, colorectal cancer ranks third in terms of incidence and the second cause of cancer-related deaths in the world. Low Anterior Resection (LAR) surgery apparently still causes postoperative complications, namely LAR Syndrome, which has an effect on a patient's quality of life ...
Yusuf Arif Bassyarah, Adeodatus Yuda Handaya, Nurcahya Setyawan, Agus Barmawi, Imam Sofii   +4 more
openaire   +1 more source

Linking Device Performance to Nanoscale Photoactivation of Grain Boundaries in 2D Hybrid Halide Perovskites

Advanced Materials Technologies, EarlyView.
The opto‐electronic response of polycrystalline (PEA)2PbBr4 thin films is investigated by correlating macroscopic photodetector performance with nanoscale mapping techniques. Grain boundary density is systematically tuned through crystallization control and linked to device responsivity.
Camilla Bordoni, Lorenzo Calcaterra, Andrea Ciavatti, Silvia Milita, Valentina Bonino, Lorenzo Margotti, Sara Cepić, Marisa Di Sabatino, Federico Boscherini, Daniela Cavalcoli, Beatrice Fraboni   +10 more
wiley   +1 more source

Implicit Prejudice and Ethnic Minorities: Arab-Muslims in Sweden [PDF]

This paper examines whether Swedish employers implicitly/automatically hold i) negative attitudes toward Arab-Muslims, an ethnic minority group subjected to substantial labor market discrimination in Sweden, and more specifically ii) associate members of
Agerström, Jens, Rooth, Dan-Olof
core  

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu, Mengqin Yuan, Yini Shang, Jiahao Chen, Fei Hou, Lihong Wang, Wei Jiang   +6 more
wiley   +1 more source

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

Advanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge, María Pagnon de la Vega, Silvia Zampar, Enrica Cerilli, Srinivas Koutarapu, Ling Wu, Paul Fraser, Sertan Arkan, Vilmantas Giedraitis, Lars Lannfelt, Greta Hultqvist, Stina Syvänen, Martin Ingelsson, Jörg Hanrieder, Dag Sehlin   +14 more
wiley   +1 more source

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

Advanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman, Lars Lau Raket, Michael Schöll, for the Alzheimer's Disease Neuroimaging Initiative†   +3 more
wiley   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Case Report: Quantitative and qualitative evaluation for electroacupuncture combined with moxibustion in the treatment of recalcitrant low anterior resection syndrome

Frontiers in Medicine
BackgroundApproximately 60–80% of rectal cancer patients develop low anterior resection syndrome (LARS) following sphincter-preserving surgery, which significantly impacts their quality of life. Existing treatments have various limitations.
Chenxi Hu, Xun Li, Lu Yang, Ruolin Fang, Jinchang Huang, Jinchang Huang, Ming Yang, Ming Yang   +7 more
doaj   +1 more source

Incidencia del Síndrome de Resección Anterior Baja tras resección de recto medido mediante LARS score y valor predictivo del POLARS score

, 2022
Grado en ...
openaire   +1 more source