Results 71 to 80 of about 1,972,994 (257)

A Portable Soft Robotic Glove with Fully Functional Thumb Assistance for Complex Dexterous Fine Motor Skills

Advanced Science, EarlyView.
A portable, sensorized, and controlled dexterous thumb‐enhanced glove helps stroke survivors swipe phones, twist caps, and perform other tasks. It is based on a powerful continuously, segmented origami dual chamber actuator to achieve active thumb CMC and MCP joint assistance and passively extend the IP joint.
Disheng Xie, Zhen Wang, Zhongping Ye, Minghao Liu, Xiangqian Shi, Shuk Fan Tong, Jianbin Liu, Chuanbin Mao, Thomas W. Leung, Haitao Liu, Raymond Kai‐yu Tong   +10 more
wiley   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Machine learning-guided prevention and management of low anterior resection syndrome: Development of an XGBoost prediction model and validation via SHAP

Laparoscopic, Endoscopic and Robotic Surgery
Objective: Colorectal cancer is among the top three cancers in terms of incidence and mortality worldwide. Although laparoscopic and robotic-assisted sphincter-preserving surgeries reduce permanent colostomy rates to under 20%, 60%–80% of patients ...
Yangtao Pan, Chaojie Huang, Xinjie Zhang, Zhentian Xu, Bingjun Bai, Min Chen, Weifeng Lao   +6 more
doaj   +1 more source

Maximizing the Energy Output of Soft Electrohydraulic Generators

Advanced Science, EarlyView.
Many energy resources cannot be viably harvested with electromagnetic generators. This article evaluates the potential of soft electrohydraulic generators as an alternative approach for energy capture. An analytical model charts their operational limits and a rigorous experimental study results in new performance benchmarks with maximum specific energy
Sophie Kirkman, Ingemar Schmidt, Lawrence T. Smith, Steven L. Zhang, Shane K. Mitchell, Soo Jin Adrian Koh, Philipp Rothemund, Christoph Keplinger   +7 more
wiley   +1 more source

Incidence of the anterior resection syndrome using low anterior resection score (LARS scale)

, 2017
Background Up to 90 % of patients undergoing low anterior resection, complain of increased daily bowel movements, urgency for defecation, and a variable degree of incontinence. A symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer has recently been validated in Lithuanian population.
Dulskas, Audrius, Smolskas, Edgaras, Kilius, Alfredas, Čižauskaitė, Agnė, Samalavičius, Narimantas Evaldas   +4 more
openaire   +1 more source

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

Monitoring the Microwave Synthesis of d0‐Free Disordered Rocksalt Cathodes Using In Situ Infrared Pyrometry

Angewandte Chemie, EarlyView.
Despite its promise for producing metastable materials, the mechanisms underlying solid‐state microwave synthesis remain poorly understood. By combining in situ thermography with x‐ray diffraction and solid‐state NMR, this study uncovers a surprising order–disorder–order reaction pathway during the microwave synthesis of the Li1.1Mn0.9O1.9F0.1${\rm Li ...
Erick A. Lawrence, Matthew A. Wright, Tianyu Li, Euan N. Bassey, Vijay Kumar, Shiyu Yuan, Yangying Zhu, Pierre‐Etienne Cabelguen, Raphaële J. Clément   +8 more
wiley   +2 more sources

Significance of tumor height, size, and Total Mesorectal Excision (TME) in the discrepancy between POLARS and actual LARS score in rectal tumors post Low Anterior Resection (LAR)

Bali Medical Journal
Background: The number of cases of rectal tumors is increasing. Currently, colorectal cancer ranks third in terms of incidence and the second cause of cancer-related deaths in the world. Low Anterior Resection (LAR) surgery apparently still causes postoperative complications, namely LAR Syndrome, which has an effect on a patient's quality of life ...
Yusuf Arif Bassyarah, Adeodatus Yuda Handaya, Nurcahya Setyawan, Agus Barmawi, Imam Sofii   +4 more
openaire   +1 more source

Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields

Advanced Science, EarlyView.
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng, Evan M. Cale, Amirabbas Maghsoudi, Matthew S. Sutton, Nancy S. Longo, Rebecca A. Gillespie, Lingshu Wang, Ivan Kosik, Sue Chong, Atsuhiro Yasuhara, Tatsiana Bylund, Arne Schön, Prabhanshu Tripathi, Yaroslav Tsybovsky, Haotian Lei, Nicholas C. Morano, Allison B. Lupatkin, Abraham J. Morton, Zabrina C. Lang, Jordan E. Becker, Isabella R. Frascilla, Myungjin Lee, Ning Li, Cuiping Liu, Ryan S. Roark, Chen‐Hsiang Shen, I‐Ting Teng, David J. Van Wazer, Danyi Wang, Lingyuan Wu, Goran Ahlsen, Mike Castro, Haijuan Du, Michael J. Ernandes, Tiansheng Li, Bob C. Lin, Mark K. Louder, Krisha McKee, Jonah S. Merriam, Sijy O'Dell, Li Ou, Sergei Pletnev, David Prikryl, Qi Qiu, Sarah Rubin, Mallika Sastry, Stephen D. Schmidt, Asif Shajahan, Andrea R. Shiakolas, Sanjay Srivatsan, Baoshan Zhang, Qiong Zhou, Mark Connors, Jason G. Gall, Yicheng Guo, Rick K. Huang, Yaoxing Huang, Richard A. Koup, Q. Paula Lei, John R. Mascola, Reda Rawi, Leonid Serebryannyy, Lawrence Shapiro, Zizhang Sheng, David D. Ho, Patrick C. Wilson, Jonathan W. Yewdell, Theodore C. Pierson, Masaru Kanekiyo, Nicole A. Doria‐Rose, Peter D. Kwong, Tongqing Zhou   +71 more
wiley   +1 more source

Diamondiyne: A 3D Carbon Allotrope With Mixed sp–sp3 Hybridization

Angewandte Chemie, EarlyView.
A new carbon allotrope with mixed sp–sp3 hybridization has been synthesized through delicately controlled kinetics at a liquid–liquid interface. The resulting material, termed diamondiyne, exhibits an expanded diamond‐type network in the form of small crystallites in a continuous all‐carbon film.
Yizhou Yang, Jie Xu, Yanyan Chen, Yu Xia, Sami Zeliouche, Clara Schäfer, Martin Ratsch, Ebba Matic, Martin Rahm, Lars Evenäs, Angela Beth Grommet, Tom Willhammar, Karl Börjesson   +12 more
wiley   +2 more sources