Results 81 to 90 of about 1,972,994 (257)
Advanced Science, EarlyView.BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai +7 more
wiley +1 more source
On‐Demand Deconstructable Thermosets Through Cleavable Comonomer and Thermolatent Base Synergy
Angewandte Chemie, EarlyView.Thermosets, valued for their chemical and mechanical properties, resist recycling due to their cross‐linked structure. Weak bonds via comonomers enable degradability, but diffusion limits effectiveness. We incorporate thermolatent bases before polymerization (thermal or 3D‐VAT printing).
Sophia Kouider +15 more
wiley +2 more sources
陆军军医大学学报Objective To investigate the influencing factors for low anterior resection syndrome (LARS) at one year after ileostomy reversal in patients who have undergone radical resection for rectal cancer, and to inform clinical interventions.
WANG Zhi, WU Wenhao, LUO Ziyan
doaj +1 more source
Advanced Science, EarlyView.Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken +8 more
wiley +1 more source
Angewandte Chemie, EarlyView.A highly versatile and general strategy is presented for the scalable production of practical quantities of ω‐substituted α‐olefins using tris(ω‐substituted alkyl)aluminum telogens that are readily available through a “green” synthesis from commodity triisobutylaluminum and ethene as the taxogen. These new α‐olefins can be designed and used as monomers
Lauren G. Logue +4 more
wiley +2 more sources
Asymptotic optimality of the quasi-score estimator in a class of linear score estimators [PDF]
, 2006 We prove that the quasi-score estimator in a mean-variance model is optimal in the class of (unbiased) linear score estimators, in the sense that the difference of the asymptotic covariance matrices of the linear score and quasi-score estimator is ...
Kukush, Alexander, Schneeweiß, Hans
core +1 more source
Supplemental Material - BIOREACTORS - PhD Thesis Lars Barthel
, 2023 This dataset contains supplemental material for the PhD thesis of Lars Barthel "Understanding the chitin synthases repertoire of the filamentous fungus Aspergillus niger" It summarises raw data recorded for stirred tank bioreactor batch cultivations ...
Barthel, Lars
core +1 more source
Fatigue‐Driven Adaptive Assistance for a Semi‐Active Upper‐Limb Occupational Exoskeleton
Advanced Intelligent Systems, EarlyView.Physical fatigue during a physical activity is estimated in real time to enable adaptive exoskeleton assistance. By continuously adjusting the level of support according to the user’s fatigue, this approach reduces physical demand and provides a pathway toward personalized exoskeleton assistance.
Seemab Zakir +6 more
wiley +1 more source
Journal of Medical Internet ResearchBackgroundPeople who undergo sphincter-preserving surgery have high rates of anorectal functional disturbances, known as low anterior resection syndrome (LARS). LARS negatively affects patients’ quality of life (QoL) and increases
Peng Zhou +9 more
doaj +1 more source
Low anterior resection syndrome after right‐ and left‐sided resections for colonic cancer
BJS Open, 2019 Background This population‐based cohort study aimed to evaluate occurrence of low anterior resection syndrome (LARS) and correlate this to health‐related quality of life in patients who had undergone segmental colonic resection for colonic cancer in the ...
C. Buchli, A. Martling, A. Sjövall
doaj +1 more source