Results 231 to 240 of about 85,533 (298)

Comprehensive tumour‐immune profiling reveals TREM2+ tumour‐associated macrophages facilitating lymph node metastasis in head and neck squamous cell carcinoma

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) TREM2+ TAMs promote CD8+ T cell exhaustion by upregulating BHLHE40 through the SPP1–CD44 axis, contributing to a suppressive tumour immune microenvironment in HNSCC. (2) CD8+ Tex induced by TREM2+ TAMs facilitates immune escape and promotes tumour cell metastasis via the lymphangion.
Zhuokai Wu   +11 more
wiley   +1 more source

Partial Laryngectomy for Thyroid Cancer: A Single Institution Case Series With Operative Techniques

open access: yesHead &Neck, Volume 48, Issue 2, Page E20-E24, February 2026.
ABSTRACT Background Partial laryngectomy has been well described as a management option for T1–3 laryngeal squamous cell cancers. However, there are a few case reports of partial laryngeal surgery for locally advanced thyroid carcinoma. Methods This is a case series of five patients with thyroid carcinoma (one primary and four recurrent) with laryngeal
Ella E. Hawes   +17 more
wiley   +1 more source

The Performance of Automatic Speaking Valves and Fixation Devices Enabling Hands‐Free Speech Following Total Laryngectomy—A Systematic Review

open access: yesHead &Neck, Volume 48, Issue 2, Page 549-569, February 2026.
ABSTRACT Background The percentage of daily automatic speaking valve use (AU) in laryngectomized patients has remained at ~25% since their invention. To increase this percentage, understanding the performance of existent devices is essential. Therefore, we reviewed studies reporting AU, fixation device lifetime (FDL), compliance, and voice and speech ...
Max J. Dullaart   +9 more
wiley   +1 more source

Longitudinal Patterns of Radiation‐Associated Dysphagia in Patients With Head and Neck Cancer: A Systematic Review

open access: yesHead &Neck, Volume 48, Issue 2, Page 597-623, February 2026.
ABSTRACT Objective To investigate the diagnostic profile of early (i.e., < 6 months of treatment) and late (i.e., ≥ 6 months of treatment) radiation‐associated dysphagia (RAD) in patients with head and neck cancer. Materials and Methods The literature was queried from inception to July 19, 2024.
Anuja H. Shah   +5 more
wiley   +1 more source

CRP and HNF1A collaborate to regulate the progression of laryngeal cancer through the Wnt signaling pathway. [PDF]

open access: yesFunct Integr Genomics
Zhao Z   +12 more
europepmc   +1 more source

Is the incidence of early‐onset cancers increasing in the northeast of Italy? A 30‐year analysis of the regional cancer registration data by age, 1987–2019

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 532-545, 1 February 2026.
Whats New? This observational study of the incidence trends of malignancy by site, stratified by age group and sex, over three decades in a large northern Italian population reveals a heterogeneous landscape among younger adults (aged under 50). Invasive cutaneous melanoma in both sexes, testicular cancer and multiple myeloma in males, and breast ...
Alessandra Buja   +9 more
wiley   +1 more source

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