Results 91 to 100 of about 18,064 (223)
CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.Using experimental models of stroke, we demonstrate that Cystatin B (CSTB) alleviates brain injury following cerebral ischemia reperfusion. This protection is mediated by inhibiting the JAK2/STAT3 signaling pathway, which reduces neuroinflammation and neuronal apoptosis. Our findings highlight CSTB as a promising therapeutic target for ischemic stroke.
Gang Zhou +9 more
wiley +1 more source
Factors influencing splanchnic microcirculation in animal models of endotoxaemia [PDF]
, 2011 Even though severe sepsis and septic shock therapy has improved in recent years, mortality remains high (22-50%). Disturbances in splanchnic organ homeostasis and increases in gut permeability have long been presumed to contribute to systemic ...
Andersson, Andreas
core +1 more source
Comprehensive Physiology, Volume 16, Issue 2, April 2026.Pancreatic exocrine microcirculation exhibits sexual dimorphism arising from steroid–genetic interactions. Laser Doppler flowmetry combined with wavelet analysis identifies a male passive coupling phenotype aligned with systemic pressure and a female active vasomotion phenotype driven by ERβ‐mediated, NO‐dependent oscillations.
Yuan Li +8 more
wiley +1 more source
Experimental and clinical application of laser doppler flowmetry in gastric and duodenal ulcerative bleedings [PDF]
Саратовский научно-медицинский журнал, 2011 The research goal is to develop a new objective diagnostic method of prerecurrence syndrome that will prognose bleeding recurrence from gastroduodenal ulcers. Materials and methods.
Afanasieva G.A. +3 more
doaj
Patologìâ, 2015 Today the diagnostics of microcirculatory disorders in patients with hypertensive nephropathy (HN) is an extremely important issue. Aim. To evaluate the functional state of hemomicrocirculatory (HMC) system and to analyze predictive capacity of ...
I. M. Fushtey , О. О. Tokarenko
doaj +1 more source
Frontiers in Physiology, 2020 Restitution of cutaneous sensory function is accomplished by neural regenerative processes of distinct mechanisms following peripheral nerve lesions. Although methods available for the study of functional cutaneous nerve regeneration are specific and ...
Szandra Lakatos +4 more
doaj +1 more source
A computational model for retinal haemodynamics under gravitational and postural variations
The Journal of Physiology, Volume 604, Issue 7, Page 2698-2716, 1 April 2026.Abstract figure legend The haemodynamic impact of gravitational and postural changes on the retina, and its relevance to spaceflight associated neuro‐ocular syndrome (SANS), remains incompletely characterized. This study assesses retinal haemodynamics from upright to head‐down tilt using a lumped‐parameter model that dynamically couples intraocular ...
Michele Nigro +2 more
wiley +1 more source
State total microcirculation in patients with hemophilia
RUDN Journal of Medicine, 2010 The paper presents the results of the study total microcirculation in patients with hemophilia, obtained using laser Doppler flowmetry. Revealed asymmetric reduction of perfusion, increase the maximum amplitude of violations of microcirculation.
I L Davidkin +4 more
doaj
[Laser Doppler blood flowmetry].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1991 Laser doppler flowmetry is a method for continuous quantification of microvascular perfusion. During the measurements, low energy Helium-Neon laser light is applied to the tissue. Doppler shifted light reflected out of the tissue is then analyzed, and the shift of frequency quantitated.
K, Kvernebo, O C, Lunde
openaire +1 more source
Animal models of ischaemic stroke and characterisation of the ischaemic penumbra [PDF]
, 2018 Over the past forty years, animal models of focal cerebral ischaemia have allowed us to identify the critical cerebral blood flow thresholds responsible for irreversible cell death, electrical failure, inhibition of protein synthesis, energy depletion ...
Arroja, Mariana M. +3 more
core +1 more source