Results 41 to 50 of about 327,567 (274)

Microbunching And Coherent Acceleration Of Electrons By Subcycle Laser Pulses [PDF]

, 1997
The pick up and acceleration of all plasma electrons irradiated by an intense, subcyclic laser pulse is demonstrated via analytical and numerical calculations.
Hojo, H., Rau, B., Tajima, T.
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Laser-plasma interaction physics for shock ignition

EPJ Web of Conferences, 2013
In the shock ignition scheme, the ICF target is first compressed with a long (nanosecond) pulse before creating a convergent shock with a short (∼100 ps) pulse to ignite thermonuclear reactions.
Goyon C., Depierreux S., Michel D.T., Loisel G., Yahia V., Masson-Laborde P.E., Loiseau P., Hüller S., Borisenko N.G., Orekhov A., Rosmej O., Nicolaï P., Tikhonchuk V.T., Labaune C.   +13 more
doaj   +1 more source

Mathematical models for laser-plasma interaction [PDF]

ESAIM: Mathematical Modelling and Numerical Analysis, 2005
Summary: We address here mathematical models related to the laser-plasma interaction. After a simplified introduction to the physical background concerning the modelling of the laser propagation and its interaction with a plasma, we recall some classical results about the geometrical optics in plasmas.
openaire   +1 more source

Effects of laser wavelength and density scalelength on absorption of ultrashort intense lasers on solid-density targets

, 2002
Hot electron temperatures and electron energy spectra in the course of interaction between intense laser pulse and overdense plasmas are reexamined from a viewpoint of the difference in laser wavelength.
Aota, Tatsuya, Kato, Susumu, Matsumoto, Yuji, Okuda, Isao, Owadano, Yoshiro, Takahashi, Eiichi   +5 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Optical probing of ultrafast laser-induced solid-to-overdense-plasma transitions

Light: Science & Applications
Understanding the solid target dynamics resulting from the interaction with an ultrashort laser pulse is a challenging fundamental multi-physics problem involving atomic and solid-state physics, plasma physics, and laser physics. Knowledge of the initial
Yasmina Azamoum, Georg Alexander Becker, Sebastian Keppler, Guillaume Duchateau, Stefan Skupin, Mickael Grech, Fabrice Catoire, Sebastian Hell, Issa Tamer, Marco Hornung, Marco Hellwing, Alexander Kessler, Franck Schorcht, Malte Christoph Kaluza   +13 more
doaj   +1 more source

Laser Shaping and Optimization of the Laser-Plasma Interaction [PDF]

, 2000
The physics of energy transfer between the laser and the plasma in laser wakefield accelerators is studied. We find that wake excitation by arbitrary laser shapes can be parameterized using the total pulse energy and pulse depletion length.
Chen, Pisin, Spitkovsky, Anatoly
core   +3 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Bright X-ray source from a laser-driven micro-plasma-waveguide

, 2015
Owing to the rapid progress in laser technology, very high-contrast femtosecond laser pulses of relativistic intensities become available. These pulses allow for interaction with micro-structured solid-density plasma without destroying the structure by ...
Pukhov, Alexander, Shen, Baifei, Thanh, Phuc Luu, Yi, Longqing   +3 more
core   +1 more source