Results 51 to 60 of about 327,567 (274)

Design considerations for the use of laser-plasma accelerators for advanced space radiation studies [PDF]

, 2012
We present design considerations for the use of laser-plasma accelerators for mimicking space radiation and testing space-grade electronics. This novel application takes advantage of the inherent ability of laser-plasma accelerators to produce particle ...
B. HIDDING, G. PRETZLER, Garrett, J. B. ROSENZWEIG, O. KARGER, T. KÖNIGSTEIN   +5 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Efficient injection of radiation-pressure-accelerated sub-relativistic protons into laser wakefield acceleration based on 10 PW lasers

, 2018
We propose a hybrid laser-driven ion acceleration scheme using a combination target of a solid foil and a density-tailored background plasma. In the first stage, a sub-relativistic proton beam can be generated by the radiation pressure acceleration in ...
Chen, M., He, M. Q., Li, Y. T., Liu, M., Sheng, Z. M., Wang, H. C., Weng, S. M., Zhang, J., Zhao, Q.   +8 more
core   +1 more source

Time evolution of stimulated Raman scattering and two-plasmon decay at laser intensities relevant for shock ignition in a hot plasma [PDF]

, 2019
Laser–plasma interaction (LPI) at intensities 1015–1016 W cm2 is dominated by parametric instabilities which can be responsible for a significant amount of non-collisional absorption and generate large fluxes of high-energy nonthermal electrons. Such a
Antonelli, L., Atzeni, S., Baffigi, F., Barbato, F., Batani, D., Boutoux, G., Cristoforetti, G., Dostal, J., Dudzak, R., D’Amato, F., Filippov, E., Gizzi, L. A., Gu, Y. J., Juha, L., Klimo, O., Krus, M., Malko, S., Mancelli, D., Martynenko, A. S., Nicolai, Ph., Ospina, V., Pikuz, S., Renner, O., Santos, J., Tikhonchuk, V. T., Trela, J., Viciani, S., Volpe, L., Weber, S.   +28 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Plasma Expansion in Laser-Target Interaction Process [PDF]

مجله علوم و فنون هسته‌ای, 2012
In this paper, the behavior of temperature, density, velocity and pressure of the plasma shock front produced by the interaction of a focused Nd:YAG laser beam on a copper target, with an average pulsewidth of 30ns and 140mJ laser energy, have been ...
A.H Farahbod, M Afshari, E Agayari
doaj  

Identification of Coupling Mechanisms between Ultraintense Laser Light and Dense Plasmas

Physical Review X, 2019
The interaction of intense laser beams with plasmas created on solid targets involves a rich nonlinear physics. Because such dense plasmas are reflective for laser light, the coupling with the incident beam occurs within a thin layer at the interface ...
L. Chopineau, A. Leblanc, G. Blaclard, A. Denoeud, M. Thévenet, J-L. Vay, G. Bonnaud, Ph. Martin, H. Vincenti, F. Quéré   +9 more
doaj   +1 more source

Microengineering Laser Plasma Interactions at Relativistic Intensities

Physical Review Letters, 2016
We report on the first successful proof-of-principle experiment to manipulate laser-matter interactions on the microscale using highly ordered Si microwire arrays. The interaction of a high contrast short pulse laser with a flat target via periodic Si microwires yields a substantial enhancement in both total and cut-off energies of the produced ...
Jiang, S., Ji, L. L., Audesirk, H., George, K. M., Snyder, J., Krygier, A., Poole, P., Willis, C., Daskalova, R., Chowdhury, E., Lewis, N. S., Schumacher, D. W., Pukhov, A., Freeman, R. R., Akli, K. U.   +14 more
openaire   +5 more sources

Plasma density measurements using chirped pulse broad-band Raman amplification [PDF]

, 2013
Stimulated Raman backscattering is used as a non-destructive method to determine the density of plasma media at localized positions in space and time. By colliding two counter-propagating, ultra-short laser pulses with a spectral bandwidth larger than ...
B. Ersfeld, D. A. Jaroszynski, G. Vieux, J. P. Farmer, Kruer W. L., M. S. Hur, R. C. Issac   +6 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source