Results 41 to 50 of about 1,851,786 (318)

LASER IRIDOTOMY [PDF]

open access: yesAustralian and New Zealand Journal of Ophthalmology, 1987
Abstract The outcome of 64 consecutive argon laser iridotomies was examined retrospectively The patients were followed for a mean of 18 months Argon laser iridotomy was shown to be effective in treating chronic angle‐closure glaucoma, those patients without field loss faring better than those with field loss 34% of the latter group eventually required ...
P, Richardson, R L, Cooper
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Enhancing laser beam performance by interfering intense laser beamlets

open access: yesNature Communications, 2019
Enhanced coupling of laser energy to the target particles is a fundamental issue in laser-plasma interactions. Here the authors demonstrate increased photon absorption leading into higher laser to electron and proton energy transfer through the ...
A. Morace   +26 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Modification of Aerosol Gold Nanoparticles by Nanosecond Pulsed-Periodic Laser Radiation [PDF]

open access: gold, 2021
Kirill Khabarov   +5 more
openalex   +1 more source

O processo sucessório e a abertura de capital nas empresas brasileiras: objetivos conflitantes

open access: yesRAE: Revista de Administração de Empresas, 1994
A abertura de capital de uma companhia pode não ser a solução adequada a problemas de sucessão em empresas familiares brasileiras.
Jairo Laser Procianoy
doaj  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Low spatial frequency laser-induced periodic surface structures in fused silica inscribed by widely tunable femtosecond laser pulses

open access: yesScientific Reports, 2022
The formation and evolution of laser-induced periodic surface structures in fused silica under irradiation of widely tunable (in the 1–3  $$\upmu$$ μ m range) linearly polarized femtosecond (200 fs) pulses was studied experimentally.
Marius Navickas   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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