Results 41 to 50 of about 2,070,930 (266)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Impact of Postoperative Intravenous Iron Therapy on Clinical Outcomes in Surgical Patients with Iron-Deficiency Anemia: A Comparative Analysis by Frailty Status in the Setting of Elective Cardiac Surgery

open access: yesMedicina
Background and Objectives: This study aimed to comparatively investigate the impact of postoperative intravenous iron therapy (IVIT) as an add-on to preoperative IVIT on clinical outcomes in frail versus non-frail patients with iron-deficiency anemia ...
Laser Şanal   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Investigations on high-power laser beam-submerged arc hybrid welding of thick duplex stainless steel using laser beam wobbling

open access: yes, 2021
Art. 042039, 9 S.Duplex stainless steels are used in many application fields due to their outstanding performance with respect to strength, toughness, and corrosion resistance.
Frank Riedel   +15 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The influence of laser assistance on the machinability of the titanium alloy Ti555-3 [PDF]

open access: yes, 2013
The Ti533-3 alloy is a new titanium alloy which is starting to see increased use in the aeronautical domain to improve the durability of components and to optimize the weight/resistance ratio. This alloy is characterized by greater resistance compared to
GERMAIN, Guénaël   +3 more
core   +1 more source

Reação dos investidores a bonificações e desdobramentos: o caso brasileiro

open access: yesRAC: Revista de Administração Contemporânea
Este artigo analisa a reação do mercado de capitais ao evento de bonificações e de desdobramentos de ações nas ações de empresas negociadas na Bolsa de Valores de São Paulo.
Kelmara Mendes Vieira   +1 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

2D longitudinal modeling of heat transfer and fluid flow during multilayered [PDF]

open access: yes, 2012
version post-print de l'article : JLA Vol : 24 Iss:3. 2D longitudinal modeling of heat transfer and fluid flow during multilayered direct laser metal deposition processDerived from laser cladding, the Direct Laser Metal Deposition (DLMD) process is ...
CARRON, Denis   +6 more
core  

O processo sucessório e a abertura de capital nas empresas brasileiras: objetivos conflitantes

open access: yesRAE: Revista de Administração de Empresas, 1994
A abertura de capital de uma companhia pode não ser a solução adequada a problemas de sucessão em empresas familiares brasileiras.
Jairo Laser Procianoy
doaj  

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