Results 71 to 80 of about 5,089,608 (342)
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
International Journal of Hyperthermia, 2019 Objective/Purpose: In order to study the effects of hyperthermia and other temperature-related effects on cells and tissues, determining the precise time/temperature course is crucial.
Yoko Miura +6 more
doaj +1 more source
Optically induced free carrier light modulator [PDF]
, 1969 Signal carrier laser beam is optically modulated by a second laser beam of different frequency acting on a free carrier source to which the signal carrier laser is directed.
Gruber, C. L., Richards, W. E.
core +1 more source
Efficient qubit detection using alkali earth metal ions and a double STIRAP process
, 2007 We present a scheme for robust and efficient projection measurement of a qubit consisting of the two magnetic sublevels in the electronic ground state of alkali earth metal ions.
Ditte Møller +6 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Magnetized fast isochoric laser heating for efficient creation of ultra-high-energy-density states
Nature Communications, 2018 It is desirable to deposit more energy in the dense plasma core to trigger the fusion ignition. Here the authors demonstrate enhanced energy coupling from laser to plasma core by using solid targets and guiding the transport of relativistic electron beam
Shohei Sakata +38 more
doaj +1 more source
Optical Fiber Amplifiers: Optimization and PerformanceEvaluation
Diyala Journal of Engineering Sciences, 2019 This work demonstrates the simulation of two different types of optical fiber amplifiers (OFA) utilizing OptiSystem–10, namely, 3 m length of erbium doped fiber amplifier (EDFA) and 7 km length of Raman fiber amplifier (RFA).
A. k. Abass +4 more
doaj +1 more source
A digital laser for on-demand laser modes [PDF]
Nature Communications, 2013 Customizing the output beam shape from a laser invariably involves specialized optical elements in the form of apertures, diffractive optics and free-form mirrors. Such optics require considerable design and fabrication effort and suffer from the further disadvantage of being immutably connected to the selection of a particular spatial mode.
Sandile, Ngcobo +3 more
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source