Results 21 to 30 of about 479 (218)

Ultra-Short Pulse Generation at 914 nm from a CW laser source [PDF]

open access: yesEPJ Web of Conferences
We present an all-PM fiber laser system seeded by a single-frequency CW laser source generating 230fs pulses at 914nm with a tunable repetition rate between 5 and 20 MHz.
Florentin Raphaël   +8 more
doaj   +1 more source

Table-top optical parametric chirped pulse amplifiers: past and present

open access: yesOpto-Electronic Advances, 2023
The generation of power- and wavelength-scalable few optical cycle pulses remains one of the major challenges in modern laser physics. Over the past decade, the development of table-top optical parametric chirped pulse amplification-based systems was ...
Audrius Dubietis, Aidas Matijošius
doaj   +1 more source

Tapered amplifier laser with frequency-shifted feedback

open access: yesSciPost Physics, 2016
We present a frequency-shifted feedback (FSF) laser based on a tapered amplifier. The laser operates as a coherent broadband source with up to 370GHz spectral width and 2.3us coherence time.
A. Bayerle, S. Tzanova, P. Vlaar, B. Pasquiou, F. Schreck
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Few-cycle Yb-doped laser sources for attosecond science and strong-field physics

open access: yesAPL Photonics
Yb-doped laser amplifiers have, in recent years, found applications in attosecond science, driven largely by the opportunities associated with high-average-power and high-repetition-rate attosecond sources.
Tran-Chau Truong   +4 more
doaj   +1 more source

Laser Active Optical Systems (LAOSs) for Material Processing

open access: yesMicromachines
The output energy of Laser Active Optical Systems (LAOSs), in which image brightness is amplified within the laser-active medium, is always higher than the input energy. This contrasts with conventional optical systems (OSs).
Vladimir Chvykov
doaj   +1 more source

Compact Aberration-Free Relay-Imaging Multi-Pass Layouts for High-Energy Laser Amplifiers

open access: yesApplied Sciences, 2016
We present the results from a theoretical investigation of laser beam propagation in relay imaging multi-pass layouts, which recently found application in high-energy laser amplifiers.
Jörg Körner   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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