Results 41 to 50 of about 272,023 (314)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

First in vitro cell co-culture experiments using laser-induced high-energy electron FLASH irradiation for the development of anti-cancer therapeutic strategies

Scientific Reports
Radiation delivery at ultrahigh dose rates (UHDRs) has potential for use as a new anticancer therapeutic strategy. The FLASH effect induced by UHDR irradiation has been shown to maintain antitumour efficacy with a reduction in normal tissue toxicity ...
Stefana Orobeti, Livia Elena Sima, Ioana Porosnicu, Constantin Diplasu, Georgiana Giubega, Gabriel Cojocaru, Razvan Ungureanu, Cosmin Dobrea, Mihai Serbanescu, Alexandru Mihalcea, Elena Stancu, Cristina Elena Staicu, Florin Jipa, Alexandra Bran, Emanuel Axente, Simion Sandel, Marian Zamfirescu, Ion Tiseanu, Felix Sima   +18 more
doaj   +1 more source

Laser-Generated Plasmas

IEEE Conference Record - Abstracts. 2005 IEEE International Conference on Plasma Science, 2005
Summary form only given. Hot plasmas can be generated by fast and intense laser pulses ablating solids placed in vacuum. A Nd:YAG laser, operating at fundamental and second harmonic, emitting 9 ns pulses with a maximum energy of 900 mJ, focused on metallic surfaces, produces high ablation yields, of the order of mug/pulse, and dense plasmas which ...
openaire   +3 more sources

Effect of the Laser Wave Front in a Laser-Plasma Accelerator [PDF]

Physical Review X, 2015
A high repetition rate electron source was generated by tightly focusing kHz, few-mJ laser pulses into an underdense plasma. This high intensity laser-plasma interaction led to stable electron beams over several hours but with strikingly complex transverse distributions even for good quality laser focal spots.
Beaurepaire, B, Vernier, A, Bocoum, M, Böhle, F, Jullien, A, Rousseau, J-P, Lefrou, T, Douillet, D., Iaquaniello, G, Lopez-Martens, Rodrigo B., Lifschitz, Agustin, Faure, Jérôme   +11 more
openaire   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

IDENTIFIKASI UNSUR NIKEL DENGAN TEKNIK LASER INDUCED PLASMA (LIP) [PDF]

, 2004
The line spectral of Ni element has been obtained for high and low concentration using Laser Induced Plasma (LIP) method. Focusing of high power pulse laser without pre treatment on the sample generates the Ni plasma contributed to atomic emission.
Kulla, Irwanuddin H., Setia Budi, Wahyu, Firdausi, K. Sofjan   +2 more
core  

Finite element analysis of laser shock peening of 2050-T8 aluminum alloy [PDF]

, 2014
Laser shock processing is a recently developed surface treatment designed to improve the mechanical properties and fatigue performance of materials, by inducing a deep compressive residual stress field.
SONG, Hongbin, JI, Vincent, Popa, Iona, PEYRE, Patrice, HFAIEDH, Neila, POPA, Ioana, VIGNAL, Vincent   +6 more
core   +1 more source

Pulsed Laser Photo-Crosslinking of Gelatin Methacryloyl Hydrogels for the Controlled Delivery of Chlorpromazine to Combat Antimicrobial Resistance

Pharmaceutics, 2022
Hydrogels are ideal candidates for the sustained local administration of antimicrobial drugs because they have customizable physicochemical properties that allow drug release kinetics to be controlled and potentially address the issue of systemic side ...
Tatiana Tozar, Simona Nistorescu, Mihai Boni, Gratiela Gradisteanu Pircalabioru, Irina Negut, Angela Staicu   +5 more
doaj   +1 more source

Laser plasma diagnostics of dense plasmas [PDF]

SPIE Proceedings, 1995
The authors describe several experiments on Nova that use laser-produced plasmas to generate x-rays capable of backlighting dense, cold plasmas (p {approximately} 1--3 gm/cm{sup 3}, kT {approximately} 5--10 eV, and areal density {rho}{ell}{approximately} 0.01--0.05 g/cm{sup 2}).
Glendinning, S. G., Amendt, P., Budil, K. S., Hammel, B. A., Kalantar, D. H., Key, M. H., Landen, O. L., Remington, B. A., Desenne, D. E.   +8 more
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source