Results 41 to 50 of about 212,842 (307)

Lunar Laser Ranging Retroreflectors: Velocity Aberration and Diffraction Pattern

The Planetary Science Journal, 2023
The Lunar Laser Ranging (LLR) retroreflector arrays have been on the Moon for half a century. During that time, the laser range uncertainty has improved by a factor of 100. Consequently, the science results have also improved by orders of magnitude.
James G. Williams, Luca Porcelli, Simone Dell’Agnello, Lorenza Mauro, Marco Muccino, Douglas G. Currie, Dennis Wellnitz, Chensheng Wu, Dale H. Boggs, Nathan H. Johnson   +9 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Tropospheric and range biases in Satellite Laser Ranging [PDF]

, 2021
Mateusz Drożdżewski, Krzysztof Sośnica   +1 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Application of A Frequency Chirped RF Intensity Modulated 532 nm Light Source in Underwater Ranging

IEEE Photonics Journal, 2020
A radio-frequency (RF) intensity-modulated light source at 532 nm was built for underwater ranging. The intensity of a narrow-linewidth laser at 1064 nm was modulated via a Mach-Zehnder electro-optical modulator.
Kun Li, Suhui Yang, Yingqi Liao, Xuetong Lin, Xin Wang, Jinying Zhang, Zhuo Li   +6 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Accuracy assessment of terrestrial laser scanning and digital close range potogrammetry for 3D cultural heritage [PDF]

, 2021
Abdullah Taha Ahmed Albourae
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

GNSS Real-Time ZTD/PWV Retrieval Based on PPP with Broadcast Ephemerides

Atmosphere
GNSS precise point positioning (PPP) plays an important role in retrieving atmospheric water vapor values and performing numerical weather prediction. However, traditional PPP relies on real-time orbits and clocks, which require continuous internet or ...
Zongqiu Xu, Shuhao Liu, Yantian Xu, Longjiang Tang, Nannan Yang, Gen Zhang   +5 more
doaj   +1 more source