DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout
A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li +12 more
wiley +1 more source
Mapping Sentinel Vessels in Uveal Melanomas Using Laser Speckle Contrast Imaging. [PDF]
Engqvist L +3 more
europepmc +1 more source
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Real-time monitoring of spinal cord hemodynamics with laser speckle contrast imaging during pedicle subtraction osteotomy in rabbits. [PDF]
Ren Z, Wang J, Ye X, Ma Y.
europepmc +1 more source
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu +15 more
wiley +1 more source
Impact of anastomotic technique and norepinephrine on microcirculation in colorectal surgery: findings from a porcine model using laser speckle contrast imaging. [PDF]
Paramasivam R +6 more
europepmc +1 more source
Designed and demonstrated a flexible metamaterial absorber via loss engineering for large‐area ultra‐broadband infrared extinction, providing a new method for miniaturization of absorbers and flexible optical devices. ABSTRACT The advancement of compact and wearable optical systems is critically limited by the lack of high‐performance, integrable ...
Zhe Wu +11 more
wiley +1 more source
Optimized laser speckle-based imaging system and methods for deep tissue cerebral blood flow imaging in small rodents. [PDF]
Paul R +6 more
europepmc +1 more source
The weakly‐solvating TFMSPyr electrolyte tailors the Li+ solvation structure by suppressing solvent coordination and promoting anion‐dominated solvation. This unique solvation environment induces preferential anion decomposition at electrode interfaces, forming robust inorganic rich S/CEI.
Bishnu P. Thapaliya +11 more
wiley +1 more source
Multidimensional Evaluation of Vascular Dysfunction in Diabetic Erectile Dysfunction: Synergistic Application of ICP Measurement, Laser Speckle Blood Perfusion Imaging, and Ex Vivo Microvascular Tension Measurement. [PDF]
Pan S +5 more
europepmc +1 more source

