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Laser Speckle Imaging to Monitor Microvascular Blood Flow: A Review
IEEE Reviews in Biomedical Engineering, 2016 Laser speckle is a complex interference phenomenon that can easily be understood, in concept, but is difficult to predict mathematically, because it is a stochastic process.
Pedro G． Vaz +2 more
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Dynamic laser speckle imaging of cerebral blood flow [PDF]
Optics Express, 2009 Laser speckle imaging (LSI) based on the speckle contrast analysis is a simple and robust technique for imaging of heterogeneous dynamics. LSI finds frequent application for dynamical mapping of cerebral blood flow, as it features high spatial and ...
P Zakharov +2 more
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A Miniaturized Platform for Laser Speckle Contrast Imaging
IEEE Transactions on Biomedical Circuits and Systems, 2012Imaging the brain in animal models enables scientists to unravel new biological insights. Despite critical advancements in recent years, most laboratory imaging techniques comprise of bulky bench top apparatus that require the imaged animals to be anesthetized and immobilized.
Janaka Senarathna +3 more
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Efficient Processing of Laser Speckle Contrast Images
IEEE Transactions on Medical Imaging, 2008Though laser speckle contrast imaging enables the measurement of scattering particle dynamics with high temporal resolution, the subsequent processing has previously been much slower. In prior studies, generating a laser speckle contrast image required about 1 s to process a raw image potentially collected in 10 ms or less.
W. James Tom +2 more
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Laser speckle imaging of blood flow in microcirculation
Physics in Medicine and Biology, 2004Monitoring the spatio-temporal characteristics of microcirculation is crucial for studying the functional activities of biotissue and the mechanism of disease. However, conventional methods used to measure blood flow suffer from limited spatial resolution or the injection of exogenous substances or the need of scanning to obtain the dynamic of regional
Haiying, Cheng +5 more
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Interferometric dynamic laser speckle imaging
Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN), 2023We developed interferometric dynamic laser speckle imaging (iDLSI) capable of three-dimensional volumetric measurements of the blood flow. Here, we present the numerical and analytical model for g2,iDLSI(τ) and perform preliminary measurement in the mouse brain.
Sharvari Zilpelwar +2 more
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Image recognition in the presence of laser speckle
Journal of the Optical Society of America A, 1986Two techniques for performing digital image recognition on speckled images are presented. The speckle is treated as a source of randomness that is used to perform Monte Carlo calculations of the correlation between an input scene and a reference scene.
Joseph Marron, G. Michael Morris
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Calibration in laser speckle contrast imaging
Biomedical Optics, 2006We provided a novel calibration procedure in laser speckle contrast imaging that can efficiently compensate systematic errors in speckle contrast caused by speckle/pixel size mismatch and static scatters in the tissue.
Shuai Yuan +2 more
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Speckle-Free Laser Imaging with Random Laser Illumination
Optics and Photonics News, 2012Spatial coherence in imaging has one notorious consequence: speckle. It corrupts images and limits laser use in applications ranging from modern microscopy to digital light projectors to photolithography. Most approaches for eliminating speckle involve time-averaging independent speckle patterns, which limits the imaging speed.
Brandon Redding +2 more
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Neurophotonics by laser speckle and photoacoustic imaging
2016 International Conference on Optical MEMS and Nanophotonics (OMN), 2016Neurophotonics involves optical techniques for brain imaging - in health and disease. This review will present two technologies, laser speckle imaging and photoacoustic imaging. Laser speckle contrast can be correlated with blood flow and therefore can be used for imaging brain blood flow and microcirculation in applications such as stroke.
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