Results 21 to 30 of about 854 (146)

The Relationship Between Treatment Satisfaction and Medication Understanding Among Patients Taking a Novel Oral Pain Reliever: A Questionnaire-Based Cross-Sectional Study [PDF]

Pain and Therapy
Introduction Patient satisfaction is important in pain management. Satisfaction with prescribed pain relievers and continued use of these drugs may be affected by a patient’s understanding of their efficacy and safety.
Makio Takahashi, Sho Kodama, Maiko Akahane, Shuhei Yamamoto, Takashi Yonemoto, Haruhiko Seki   +5 more
doaj   +2 more sources

Lasmiditan and Different Triptans in Menstrual Migraine: A Bayesian Network Meta-analysis [PDF]

Pain and Therapy
Introduction Menstrual migraine (MM) is a common subtype of migraine that greatly affects a woman's quality of life. A number of different drugs are used to treat menstrual migraine, but it is not known which is more effective.
Zhaoming Song, Yanao Guo, Jingyu Gu, Chen Yang, Ruisi Qu, Jian Li, Zhouqing Chen, Zhong Wang   +7 more
doaj   +2 more sources

Profile of Lasmiditan in the Acute Treatment of Migraine in Adults: Design, Development, and Place in Therapy

Drug Design, Development and Therapy, 2023
Christopher C Anderson,* Juliana H VanderPluym* Department of Neurology, Mayo Clinic, Scottsdale, AZ, USA*These authors contributed equally to this workCorrespondence: Juliana H VanderPluym, Department of Neurology, Mayo Clinic, 13400 E Shea ...
Christopher C Anderson
exaly   +2 more sources

Real-world effectiveness and safety of lasmiditan in patients with migraine: an observational study [PDF]

Frontiers in Neurology
ObjectiveTo evaluate the real-world effectiveness and safety of lasmiditan and determine the factors associated with its effectiveness and adverse effects.MethodsWe evaluated 75 migraine patients (15 males and 60 females; age 44.0 ± 12.4 years ...
Saro Kobayashi, Saro Kobayashi, Shiho Suzuki, Mukuto Shioda, Tomohiko Shiina, Hiroaki Fujita, Hirotaka Sakuramoto, Ryotaro Hida, Keisuke Suzuki   +8 more
doaj   +2 more sources

The impact of headache specialist density and the introduction of gepants and lasmitidan on prescriptions for acute migraine treatments: a regression and interrupted time series analysis [PDF]

Frontiers in Neurology
BackgroundUnderstanding all factors that affect a patient’s acute migraine treatment care is crucial. We sought to determine the impact of headache specialist density and the introduction of the gepants and lasmiditan on the prescription of acute ...
Leon S. Moskatel, Rebecca Y. Linfield, Niushen Zhang   +2 more
doaj   +2 more sources

5-HT1F receptor agonism induces mitochondrial biogenesis and increases cellular function in brain microvascular endothelial cells [PDF]

Frontiers in Cellular Neuroscience
IntroductionVascular and mitochondrial dysfunction are well-established consequences of multiple central nervous system (CNS) disorders, including neurodegenerative diseases and traumatic injuries.
Natalie E. Scholpa, Natalie E. Scholpa, Epiphani C. Simmons, Epiphani C. Simmons, Austin D. Thompson, Austin D. Thompson, Austin D. Thompson, Seth S. Carroll, Rick G. Schnellmann, Rick G. Schnellmann, Rick G. Schnellmann, Rick G. Schnellmann, Rick G. Schnellmann   +12 more
doaj   +2 more sources

Long-term treatment with lasmiditan in patients with migraine: post hoc analysis of treatment patterns and outcomes from the open-label extension of the CENTURION randomized trial [PDF]

The Journal of Headache and Pain
Background The objective of this analysis was to gain new insights into the patient characteristics and other factors associated with lasmiditan usage and clinical outcomes under conditions resembling the real-world setting.
Mika Komori, Akichika Ozeki, Yuka Tanji, Eriko Kamiki, John H. Krege, Lily Qian Li, Shiho Suzuki, Mamoru Shibata, Takao Takeshima   +8 more
doaj   +2 more sources

Lasmiditan mechanism of action – review of a selective 5-HT1F agonist [PDF]

The Journal of Headache and Pain, 2020
Migraine is a leading cause of disability worldwide, but it is still underdiagnosed and undertreated. Research on the pathophysiology of this neurological disease led to the discovery that calcitonin gene-related peptide (CGRP) is a key neuropeptide ...
David B. Clemow, Kirk W. Johnson, Helen M. Hochstetler, Michael H. Ossipov, Ann M. Hake, Andrew M. Blumenfeld   +5 more
doaj   +2 more sources

The pharmacological profile and clinical prospects of the oral 5-HT1F receptor agonist lasmiditan in the acute treatment of migraine

Therapeutic Advances in Neurological Disorders, 2015
More than 20 years have passed without the launch of a new substance class for acute migraine therapy. Triptans were the latest class of substances which successfully passed all developmental stages with a significant antimigraine efficacy and a ...
Uwe Reuter, Heike Israel, Lars Neeb
doaj   +2 more sources

Lasmiditan for the treatment of acute migraine: a review and potential role in clinical practice

Journal of Pain Research, 2018
Jessica C Oswald, Nathaniel M Schuster UCSD Center for Pain Medicine, La Jolla, CA, USA Abstract: Now that the vascular hypothesis of migraine is no longer the prevailing theory of migraine pathogenesis, there is interest in developing acute migraine ...
Oswald JC, Schuster NM
doaj   +1 more source