Results 41 to 50 of about 13,667 (181)

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

Effects of Cellulase and Lactobacillus plantarum Supplementation on Fermentation Characteristics, In Situ Degradability, and Microbial Community Dynamics of Apple Pomace Silage

Animal Research and One Health, EarlyView.
This study aimed to investigate the effects of cellulase and Lactobacillus plantarum on the silage quality, in situ digestibility, and microbial communities of apple pomace silage. The combined supplementation of cellulase and Lactobacillus plantarum in apple pomace silage improved fermentation quality and enhanced rumen utilization efficiency.
Zhuangzhuang Liu, Xiongfei Zhang, Fengbo Sun, Junhu Yao, Xinjian Lei   +4 more
wiley   +1 more source

A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection

Nature Communications, 2023
Lassa virus is a member of the Arenaviridae family, which causes human infections ranging from asymptomatic to severe hemorrhagic disease with a high case fatality rate.
Adam J. Ronk, Nicole M. Lloyd, Min Zhang, Caroline Atyeo, Hailee R. Perrett, Chad E. Mire, Kathryn M. Hastie, Rogier W. Sanders, Philip J. M. Brouwer, Erica Olmann Saphire, Andrew B. Ward, Thomas G. Ksiazek, Juan Carlos Alvarez Moreno, Harshwardhan M. Thaker, Galit Alter, Sunny Himansu, Andrea Carfi, Alexander Bukreyev   +17 more
doaj   +1 more source

Pathogens that Cause Illness Clinically Indistinguishable from Lassa Fever, Nigeria, 2018

Emerging Infectious Diseases, 2022
During the 2018 Lassa fever outbreak in Nigeria, samples from patients with suspected Lassa fever but negative Lassa virus PCR results were processed through custom gene expression array cards and metagenomic sequencing.
Jonathan W. Ashcroft, Adebola Olayinka, Nnaemeka Ndodo, Kuiama Lewandowski, Martin D. Curran, Chioma Dan Nwafor, Kingsley Madubuike, Helen Bagnall, Abdulmajid S. Musa, Adama Ahmad, Afolabi Akinpelu, Adesola Adeleye, Chukwuji Martin, Adejoke Akano, Michael Onoja, Akanimo Iniobong, Winifred Ukponu, Chinedu Arinze, Else Ilori, Nwando Mba, Benedict Gannon, Anthony Ahumibe, Chikwe Ihekweazu   +22 more
doaj   +1 more source

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

Animal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li, Yuchen He, Yangshuo Hu, Naominggaowa, Huaiqiang Yang, Zhu Meng, Fei Liu, Shiwen Zhang, Yi Jin, Mingxing Chu, Zhangyuan Pan   +10 more
wiley   +1 more source

Evidence to Impact Pathways: Strengthening Policy Coherence for Sustainable Development

The Journal of Indonesia Sustainable Development Planning
This issue features 15 articles, including a commentary and a book review. The research papers are organized into eight thematic clusters, covering topics such as decentralisation, fiscal transfers, and governance; sustainability assessments in agri-food
Jonatan Lassa
doaj   +1 more source

Use of Favipiravir to Treat Lassa Virus Infection in Macaques

Emerging Infectious Diseases, 2018
Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection.
Kyle Rosenke, Heinz Feldmann, Jonna B. Westover, Patrick William Hanley, Cynthia Martellaro, Friederike Feldmann, Greg Saturday, Jamie Lovaglio, Dana P. Scott, Yousuke Furuta, Takashi Komeno, Brian B. Gowen, David Safronetz   +12 more
doaj   +1 more source

Lassa antiviral LHF-535 protects guinea pigs from lethal challenge

Scientific Reports, 2022
LHF-535 is a small molecule antiviral currently in development for the treatment of Lassa fever, a zoonotic disease endemic in West Africa that generates significant morbidity and mortality.
Kathleen A. Cashman, Eric R. Wilkinson, Jeffrey Posakony, Ikenna G. Madu, Eric J. Tarcha, Kurt H. Lustig, Marcus J. Korth, Kristin M. Bedard, Sean M. Amberg   +8 more
doaj   +1 more source

Closed‐form stress solution and minimum safe burial depth correction for shallow‐buried large‐diameter energy storage chambers

Deep Underground Science and Engineering, EarlyView.
This study develops a closed‐form solution for stress analysis of shallow‐buried large‐diameter compressed air energy storage (CAES) chambers, explicitly incorporating free surface, lateral pressure, and gravity gradient effects. Validated against numerical simulations, the solution accurately captures stress redistribution and reveals upward migration
Zeyuan Sun, Cheng Zhao, Jinquan Xing
wiley   +1 more source

Incidence of symptomatic Lassa virus infection in West African countries (Enable 1.0 Lassa Research Study): a prospective, multisite, cohort study

The Lancet Global Health
Summary: Background: Lassa fever vaccine trials are hampered by knowledge gaps on disease incidence, at-risk populations, sequelae, and transmission risks.
Abdel Mecit Dicko Issifou, Akpenè Ruth Esperencia Deha, Anges Yadouleton, Ansia Isiace Yanclo, Ayola Akim Adegnika, Carine Tchibozo, Enagnon Junior Juvenal Prince Honvou, Enagnon Parsifal Marie Alexandre Logbo, Francis Houeya, Gildas Hounkanrin, Jeannot Zinsou, Josiane Honkpehedji, Olaniyi Abil Adegnika, Olouyomi Scherif Adegnika, Praise Adewumi, Selidji Todagbe Agnandji, Yvette Badou, Adebola Olayinka, David Dogo, Kamji Jan, Khadijah Ojirobe, Lynn Sase, Michael Adebisi, Onikepe Folarin, Adama Ahmad, Adesola Adeleye, Chiedozie Ojide, Chima Ihemeje, Eugene Samuel Bwede, Iliya Botson, Jessica Onyema, Munzali Shamsu, Nkiruka Lynda Uzoebo, Osarenmwinda Omobude, Sa’adatu Aliyu Abubakar, Zacchaeus Adejuyigbe, Abdel Mécit Odia Ikponwonsa, Cyril Erameh, Danny Asogun, Ekaete Tobin, Ephraim Ogbaini-Emovon, Esther Okogbenin, Faustina Blackie, Francis Erah, George Akpede, Gloria Eifediyi, Ivie Airefetalor, Jacqueline Ehimuan, Joseph Okoeguale, Martha Okonofua, Maxy Odike, Monday Agbonifo, Nosa Akpede, Reuben Eifediyi, Sylvanus Okogbenin, Austin A Osagbaekhoe, Bamidele Funbi, Chukwuyem Abejegah, Ireneh Ronke, Johnson Etafo, Liasu Adeagbo Ahmed, Macdonald Onyechi, Nelson A Adedosu, Oladele Oluwafemi Ayodeji, Andrea Bernasconi, Matthias Borchert, Abu Augustine, Benedict N Azuogu, Chiedozie Ojide, Ekeh Matthew, Ifeanyi Nwator, Ngozo Ugwu, Nnenna Ajayi, Odeh Elizabeth, Okoro Sylvanus, Onoh Robinson, Rosemary Duruiheoma, Venatious Onyia, Aminata Ndiaye, Anton Camacho, Boni-Maxime Ale, Denis Opio, Eric Youm, Hugo Soubrier, Mark Ndifon, Patrick Barks, Paul Campbell, Robert Nsaibirni, Souna Garba, Yves Amevoin, Christine Jacobsen, Elisabeth Fichet Calvet, Guiditta Annibaldis, Nathalie J Vielle, Ndapewa Ithete, Sophie Duraffour, Stephan Günther, Abigail Morrison, Alexander Samposon, Alfred Flomo, Aloysius Weah Duke, Amara Fofana, Carwolo Peru, Catherine Nimely, Catherine Sumo, David A Wohl, Emmanuel Kerkula, Hanan Shuayto, Jean Demarco, Jefferson Sibley, Laurel Zdanski, Eleanor Watts, Sam Livingston, Sandrena Frischer, Stanley Kerkula, Susan Sunay, Thomas Remont, Thomas Sumo, William A Fischer, II, David A Wohl, McKenzie Colt, Crystal Y Zheng, Emily J Engel, John S Schieffelin, Nell G Bond, Robert F Garry, Alhaji Jalloh, Donald Samuel Grant, Foday Alhasan, John D Sandi, Lansana Kanneh, Mambu Momoh, Mohamed Harding, Mohamed K Saio, Robert Samuels, Tiangay Kallon, Christian T Happi, Onikepe Folarin, Carol Kagia, Patrick Suykerbuyk, Suzanne Penfold, Aissatou Bah, Amadou Dore, Bakary Sylla, Barrè Soropgui, Fanta Berete, Jacob Camara, Moussa Conde, N’Faly Magassouba, Lisa Elisabeth Diallo, Margaret Williams, Philip Ayivor, Ahmadou Dore, Alpha Mamodou Diallo, Alpha Midiaou Sow, Bakary Sylla, Gnoumé Camara, Jacob Camara, Mamadou Lamine Barry, Moussa Conde, Moussa Soka Douno, Tamba Jacques Millimouno, Dory Kovacs, J Gabrielle Breugelmans, Henshaw Mandi, Roice Fulton, Solomon Abebe Yimer, Sophie Warren   +167 more
doaj   +1 more source