Results 131 to 140 of about 253,016 (276)

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

open access: yesAnimal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang   +3 more
wiley   +1 more source

Regularization Paths for Generalized Linear Models via Coordinate Descent

open access: yesJournal of Statistical Software, 2010
We develop fast algorithms for estimation of generalized linear models with convex penalties. The models include linear regression, two-class logistic regression, and multi- nomial regression problems while the penalties include ℓ1 (the lasso), ℓ2 (ridge
Jerome Friedman   +2 more
doaj  

Automated Feature Extraction and Classification of Submerged Cultural Heritage Assets in the Puck Lagoon via Multisensor Remote Sensing

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT This study presents a strong framework for the detection and classification of Submerged Cultural Heritage Assets (SCHA) in shallow marine environments using the integration of multibeam echosounder and airborne LiDAR bathymetry with object‐based image analysis and fuzzy logic–based classification.
Łukasz Janowski   +4 more
wiley   +1 more source

The Layout and Size of an Early Pre‐Pottery Neolithic B Small Settlement Revealed by Geophysical Prospection at Harbetsuvan Tepesi in Southeastern Anatolia

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT In Upper Mesopotamia, the transition from the Pre‐Pottery Neolithic A (PPNA) to Pre‐Pottery Neolithic B (PPNB) period, ca. 10 800–10 600 cal. BP, is marked by a series of changes in chipped stone industries, architectural forms, symbolic objects, regional distribution of settlements and long‐distance exchange networks among others.
Toshihiro Tada   +7 more
wiley   +1 more source

Arthroscopic Posterior Labral Repair in Professional Contact Athletes Restores Shoulder Stability and Enables Successful Return to Pre‐injury Competition

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate return‐to‐competition rates, posterior shoulder instability recurrences, and revision surgeries following arthroscopic posterior labral repair in this elite cohort. Methods A retrospective review of prospectively collected data included professional contact athletes undergoing primary arthroscopic posterior labral repair by a single
Ayham Jaber   +6 more
wiley   +1 more source

Multimodal Integration of Protein Interactomes With Genomic and Molecular Data Discovers Distinct Rheumatoid Arthritis Endotypes

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is a heterogeneous autoimmune disease characterized by clinical and molecular heterogeneity, notably in the presence of anti–cyclic citrullinated peptide (CCP) antibodies. Patients with CCP+ RA exhibit more severe disease progression and distinct treatment responses compared to patients with CCP− RA.
Javad Rahimikollu   +10 more
wiley   +1 more source

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

open access: yesArthritis &Rheumatology, EarlyView.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun   +13 more
wiley   +1 more source

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