Results 141 to 150 of about 253,016 (276)

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera   +84 more
wiley   +1 more source

Development of a web-based machine learning model for early prediction of delayed high-dose methotrexate clearance in pediatric osteosarcoma. [PDF]

Front Pediatr
Duan F, Ji M, Wu L, Liu C.
europepmc   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Assessment of Lasso and Ridge models for soil swelling potential prediction. [PDF]

Sci Rep
Bility MT, Vora T, Lakhani PN, Bhogayata AC, Bhagat SK.   +4 more
europepmc   +1 more source

Effective Performance of the 2022 American College of Rheumatology/EULAR Classification Criteria for Antineutrophil Cytoplasmic Antibody–Associated Vasculitis in Pediatric Patients: An ARChiVe Study

Arthritis &Rheumatology, EarlyView.
Objective To assess the 2022 American College of Rheumatology (ACR)/EULAR classification criteria for antineutrophil cytoplasmic antibody–associated vasculitis (AAV) in children with chronic small‐to‐medium vessel vasculitis. Methods A cohort of 574 patients, identified by physician's diagnosis (MD‐diagnosis) in A Registry of Childhood Vasculitis, was ...
David A. Cabral, Else S. Bosman, Nick McPhate, Simranpreet K. Mann, Kirandeep K. Toor, Kimberly A. Morishita, Raashid Luqmani, Michael W. Beresford, James Bistolarides, Sarah Campillo, Sirirat Charuvanij, Kathryn Cook, Paul Dancey, Marietta de Guzman, Samundeeswari Deepak, Barbara Eberhard, Melissa Elder, Samuel Gagne, Katie Harrison, Adam Huber, Archana Khan, Susan Kim, Marisa S. Klein‐Gitelman, Tzielan C. Lee, Suzanne C. Li, Neil Martin, Flora McErlane, L. Nandini Moorthy, Alvaro H. Orjuela, Jonathan Park, Phil Riley, Alan M. Rosenberg, Susan Shenoi, Vidya Sivaraman, Sodality Sutnga, Tamara Tanner, Stacey E. Tarvin, Marinka Twilt, Linda Wagner‐Weiner, Rae S. M. Yeung, Kelly L. Brown, for the ARChiVe Investigators Network within the PedVas Initiative   +41 more
wiley   +1 more source

Dual-probe genome mining identifies citrulassin N, a novel citrulline modified lasso peptide from <i>Streptomyces</i> sp. NAX00255. [PDF]

Front Microbiol
Wang ZR, Zeng C, Yan ZY, Xu ZF, Feng D.
europepmc   +1 more source

Performance improvement of discrete‐time linear‐quadratic regulators applied to uncertain linear systems using the Tikhonov regularization method

Asian Journal of Control, EarlyView.
Abstract The linear‐quadratic regulator (LQR) problem of optimal control of an uncertain discrete‐time linear system (DTLS) is revisited in this paper from the perspective of Tikhonov regularization. We show that an optimally chosen regularization parameter reduces, compared to the classical LQR, the values of a scalar error function, as well as the ...
Fernando Pazos, Amit Bhaya
wiley   +1 more source

Prognostic and predictive value of radiomics-based imaging features in patients with colorectal liver metastasis receiving radioembolisation in first-line setting. [PDF]

Eur J Radiol Open
Öcal O, Stüber AT, Abacı G, Wildgruber M, Mansour N, Deniz S, Puhr-Westerheide D, Fabritius MP, Ricke J, Ingrisch M, Seidensticker M.   +10 more
europepmc   +1 more source

Arthroscopic‐Assisted Suture Tape–Reinforced Triangular Fibrocartilage Complex Repair and Distal Radioulnar Ligament Augmentation Using a Modified Adams‐Berger Technique

Arthroscopy Techniques, EarlyView.
Abstract Distal radioulnar joint instability secondary to triangular fibrocartilage complex (TFCC) injury remains a major challenge in wrist surgery. Traditional tendon graft–based reconstruction techniques, such as the Adams‐Berger procedure, though effective, require extensive soft tissue dissection and tendon harvesting, resulting in significant ...
Jin‐Ming Zhang, Hao‐Yang Tan, Xing‐Hao Deng, Shu‐Bo Li, Jian‐Zhong Xie, Yaxiang Liu, Zhong Chen   +6 more
wiley   +1 more source

Hybrid models of sparse and robust regression to solve heterogeneity problem in black pepper big data. [PDF]

Sci Rep
Kumar PR, Ibidoja OJ, Ali MKM, Ishak WRW.   +3 more
europepmc   +1 more source