Geochemical evidence for the origin of late Quaternary loess, Seward Peninsula, Alaska
Arctic, Antarctic, and Alpine ResearchLoess is the most widespread surficial deposit in the state of Alaska. Although loess of last glacial age is common in mid-continental North America, records of last glacial loess in Alaska have been elusive. Here we report a record of last glacial loess
Daniel R. Muhs, Jeffrey S. Pigati
doaj +1 more source
Frontiers in Earth Science, 2016 Waxing/waning of the ice sheets and the associated change in thermohaline circulation have played an important role in global climate change since major continental ice sheets appeared in the northern hemisphere about 2.75 million years ago.
Masao eOhno +8 more
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Rain driven by receding ice sheets as a cause of past climate change [PDF]
, 2009 The Younger Dryas cold period, which interrupted the transition from the last ice age to modern conditions in Greenland, is one of the most dramatic incidents of abrupt climate change reconstructed from paleoclimate proxy records. Changes in the Atlantic
Bitz, Cecilia M. +2 more
core +1 more source
A tropical speleothem record of glacial inception, the South American Summer Monsoon from 125 to 115 ka [PDF]
Climate of the Past, 2015 Relatively few marine or terrestrial paleoclimate studies have focused on glacial inception, the transition from an interglacial to a glacial climate state.
S. J. Burns +3 more
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Hydrology and climatology at Laguna La Gaiba, lowland Bolivia: complex responses to climatic forcings over the last 25,000 years [PDF]
, 2014 Diatom, geochemical and isotopic data provide a record of environmental change in Laguna La Gaiba, lowland Bolivia, over the last ca. 25 000 years. High-resolution diatom analysis around the last glacial–interglacial transition provides new insights into
Fitzpatrick, K.A. +6 more
core +2 more sources
The key role of topography in altering North Atlantic atmospheric circulation during the last glacial period [PDF]
, 2011 The Last Glacial Maximum (LGM; 21 000 yr before present) was a period of low atmospheric greenhouse gas concentrations, when vast ice sheets covered large parts of North America and Europe.
C. Li +4 more
core +4 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Assessment of sea surface temperature changes in the Gulf of Cadiz during the last 30 ka: implications for glacial changes in the regional hydrography [PDF]
Biogeosciences, 2011 New dinocyst analyses were conducted on core MD99-2339 retrieved from the central Gulf of Cadiz. Dinocyst and foraminiferal assemblages from this core are combined with existing data off SW Portugal and NW Morocco to investigate past hydrological and ...
A. Penaud +8 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source