Results 41 to 50 of about 160,902 (289)

Millennial-scale interaction between ice sheets and ocean circulation during marine isotope stage 100

open access: yesFrontiers in Earth Science, 2016
Waxing/waning of the ice sheets and the associated change in thermohaline circulation have played an important role in global climate change since major continental ice sheets appeared in the northern hemisphere about 2.75 million years ago.
Masao eOhno   +8 more
doaj   +1 more source

The last glacial cycle: transient simulations with an AOGCM [PDF]

open access: yes, 2012
A number of transient climate runs simulating the last 120kyr have been carried out using FAMOUS, a fast atmosphere-ocean general circulation model (AOGCM).
Gregory, Jonathan, Smith, Robin
core   +1 more source

Reduced plant water status under sub-ambient pCO2 limits plant productivity in the wild progenitors of C3 and C4 cereals. [PDF]

open access: yes, 2016
BACKGROUND AND AIMS: The reduction of plant productivity by low atmospheric CO2 partial pressure (pCO2) during the last glacial period is proposed as a limiting factor for the establishment of agriculture.
Colin P. Osborne   +5 more
core   +1 more source

A tropical speleothem record of glacial inception, the South American Summer Monsoon from 125 to 115 ka [PDF]

open access: yesClimate of the Past, 2015
Relatively few marine or terrestrial paleoclimate studies have focused on glacial inception, the transition from an interglacial to a glacial climate state.
S. J. Burns   +3 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Progress in palynology of the Gelasian–Calabrian Stages in Europe: Ten messages [PDF]

open access: yes, 2007
Europe has at present the most extensive network of palynological sites covering the Late Pliocene and the Early Pleistocene or roughly the Gelasian-Calabrian Stages. This paper covers ten points of recent progress in the palynology of this time period:
Leroy, SAG
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Assessment of sea surface temperature changes in the Gulf of Cadiz during the last 30 ka: implications for glacial changes in the regional hydrography [PDF]

open access: yesBiogeosciences, 2011
New dinocyst analyses were conducted on core MD99-2339 retrieved from the central Gulf of Cadiz. Dinocyst and foraminiferal assemblages from this core are combined with existing data off SW Portugal and NW Morocco to investigate past hydrological and ...
A. Penaud   +8 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Phytoliths and Pollen from a Desert Wetland Through the Last Glacial–Interglacial Cycle in Azraq, Jordan

open access: yesQuaternary
Phytoliths, pollen, and spores in a stratigraphic sequence from the Shishan Wetland (Azraq Basin, Jordan) and supported by modern pollen and phytolith data provide information on vegetation, climatic trends, and the influence of fire through MIS 2 and ...
Carlos E. Cordova   +7 more
doaj   +1 more source

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