Results 41 to 50 of about 11,700 (225)

Safety, tolerability, and efficacy of fixed combination therapy with dorzolamide hydrochloride 2% and timolol maleate 0.5% in glaucoma and ocular hypertension. [PDF]

, 2010
Glaucoma is a collection of diseases characterized by multifactorial progressive changes leading to visual field loss and optic neuropathy most frequently due to elevated intraocular pressure (IOP).
Bell, Nicholas P, Feldman, Robert M, Ramos, José L   +2 more
core   +3 more sources

A 4-week, dose-ranging study comparing the efficacy, safety and tolerability of latanoprost 75, 100 and 125 μg/mL to latanoprost 50 μg/mL (xalatan) in the treatment of primary open-angle glaucoma and ocular hypertension

BMC Ophthalmology, 2012
Background Several studies have investigated the effect of latanoprost on intraocular pressure (IOP). We compared the IOP-lowering effects of three higher concentrations of latanoprost with the commercially available concentration of 0.005% (50 μg/mL) in
Eveleth David, Starita Carla, Tressler Charles   +2 more
doaj   +1 more source

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

Arthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Latanoprost with high precision, piezo-print microdose delivery for IOP lowering: clinical results of the PG21 study of 0.4 µg daily microdose. [PDF]

, 2018
Background:Topical high-precision piezo-print delivery of microdoses of latanoprost achieved significant IOP reduction consistent with the eyedropper effect but with a 75% reduced exposure to drugs and preservatives.
Ianchulev, Tsontcho, Kramm, Robert L, Lin, Shan, Pasquale, Louis R, Tsai, James C, Weinreb, Robert N   +5 more
core  

Safety and efficacy of travoprost solution for the treatment of elevated intraocular pressure [PDF]

, 2015
Travoprost is a prostaglandin analogue widely used for reducing intraocular pressure (IOP) in patients affected with glaucoma and ocular hypertension. It exerts its ocular hypotensive effect through the prostaglandin FP receptors, located in the ciliary ...
Centofanti, Marco, Floriani, Irene, Katsanos, Andreas, Konstas, Anastasios, Quaranta, Luciano, Riva, Ivano   +5 more
core   +2 more sources

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

Epilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei, Rachel Yui Ki Chu, Rachel Lancey Lai, Florinda Hui‐Ning Chu, Ian Yu Hin Leung, William Chun Yin Leung, Franco Wing Tak Cheng, Thomas Chi Ho Lam, Ian Chi Kei Wong, Esther Wai Yin Chan, Francisco Tsz Tsun Lai   +10 more
wiley   +1 more source

Persistence on prostaglandin ocular hypotensive therapy: an assessment using medication possession and days covered on therapy [PDF]

, 2010
BACKGROUND:Prior research has demonstrated that medication persistence (continued acquisition of therapy over time) is far from optimal among patients with glaucoma.
Kotak, Sameer, Reardon, Gregory, Schwartz, Gail   +2 more
core   +2 more sources

Traction suture fixation technique using a capsular tension ring fragment for severe lens displacement during cataract surgery in dogs

Veterinary Ophthalmology, Volume 28, Issue 2, Page 197-206, March 2025.
Abstract Objectives To describe the traction suture fixation technique for severely displaced lenses (≥180°) using a capsular tension ring (CTR) fragment during cataract surgery in dogs, and to retrospectively investigate its clinical outcomes. Animals Studied Eight dogs (nine eyes). Procedures The medical records of dogs with severe lens displacement (
Shinya Fukumoto, Tomomi Minamoto
wiley   +1 more source

Topical latanoprost does not cause macular thickening after uncomplicated cataract surgery. [PDF]

, 2012
PurposeTo explore changes in central macular thickness (CMT) after a two-month period of glaucoma therapy with topical latanoprost after uneventful phacoemulsification.MethodsForty-one eyes of 31 patients with primary open angle or pseudoexfoliative ...
Amini, Heydar, Eslami, Yadollah, Fakhraie, Ghasem, Latifi, Golshan, Moghimi, Sasan, Nouri-Mahdavi, Kouros, Zandian, Mehdi, Zarei, Reza   +7 more
core   +1 more source