We determined a comprehensive immunohistochemistry of putative isoforms of enzymes for prostaglandin (PG) F2α and PGE2 biosynthesis and these PGs levels in placenta and fetal membrane of normal pregnant rats in vivo. Placenta and fetal membrane showed positive immunoreactions for phospholipase A2 group 4A, but not group 2A, and cyclooxygenase (COX)-1 ...
SATOH, Hironori +3 more
openaire +4 more sources
Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. [PDF]
The contribution of inflammation to the pathogenesis of tendinopathy and high prevalence of re-injury is not well established, although recent evidence suggests involvement of prostaglandins.
Stephanie Georgina Dakin +5 more
doaj +1 more source
Aspirin treatment of mice infected with Trypanosoma cruzi and implications for the pathogenesis of Chagas disease. [PDF]
Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate host response and disease progression.
Shankar Mukherjee +13 more
doaj +1 more source
EFFECT OF VERAPAMIL ON THE PULMONARY VASOCONSTRICTOR ACTION OF PROSTAGLANDIN F2α AND A SYNTHETIC PGH2 ANALOGUE [PDF]
The vasopressor response to prostaglandin F2α (PGF2α) and to ((15S)‐hydroxy‐11α, 9α‐(epoxymethano)‐prosta‐5Z, 13E‐dienoic acid) (U‐46619) in the canine isolated lung lobe was significantly attenuated following the administration of verapamil. The pressor response to arachidonic acid (AA) was not affected by the presence of verapamil.
A D, Angerio +4 more
openaire +2 more sources
Actomyosin-Driven Division of a Synthetic Cell [PDF]
One of the major challenges of bottom-up synthetic biology is rebuilding a minimal cell division machinery. From a reconstitution perspective, the animal cell division apparatus is mechanically the simplest and therefore attractive to rebuild.
Lucia Baldauf +3 more
semanticscholar +1 more source
Synthetic Biology Toolbox for Nitrogen-Fixing Soil Microbes.
The soil environment adjacent to plant roots, termed the rhizosphere, is home to a wide variety of microorganisms that can significantly affect the physiology of nearby plants.
Maya Venkataraman +6 more
semanticscholar +1 more source
OBJETIVO: Avaliar o custo ao final de 5 anos, a efetividade e a relação custo-efetividade das associações fixas de prostaglandina ou prostamida com timolol 0,5% para o tratamento do glaucoma e da hipertensão ocular no Estado de Minas Gerais, Brasil ...
Ricardo Augusto Paletta Guedes +3 more
doaj +1 more source
Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes [PDF]
Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition.
Aardema +49 more
core +2 more sources
Functional characterization of synthetic leukotriene B and its stereochemical isomers. [PDF]
Leukotriene B (LTB), a potent lipid chemotactic factor for neutrophils, is 5S,12R-dihydroxy-6,14-cis,8,10-trans-eicosatetraenoic acid (Fig 1), based upon direct comparison of natural LTB with synthetic 5S,12R-dihydroxy-6,8,10,14-eicosatetraenoic acid (5 ...
Austen, K +5 more
core +1 more source
Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico +8 more
core +1 more source

