Collision-Induced Gas-Phase Reactions of PFB-TMS Derivatives of F2-Prostaglandins in Quadrupole GC-NICI-MS/MS: A Mini-Review and a Meta-Analysis [PDF]
MoleculesArachidonic acid (eicosatetraenoic acid) is the precursor of the eicosanoids, which include prostaglandins (PG). Methods based on GC-MS/MS are the Gold Standard for the quantitative analysis of eicosanoids in biological samples.
Dimitrios S. Tsikas, Stefanos A. Tsikas
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PROSTAGLANDINS F AND OVULATION IN MICE [PDF]
Reproduction, 1974 Prostaglandins (PGs) are known to exert profound physiological and pharmacological effects on the female reproductive system in women and in many other species (Weeks, 1972; Labhsetwar, 1974). Indomethacin and aspirin, inhibitors of prostaglandin biosynthesis, block PMSG-induced ovulation in immature (Armstrong & Grinwich, 1972; Orczyk & ...
I F, Lau, S K, Saksena, M C, Chang
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Prostaglandins E and F in Endocrine Diarrheagenic Syndromes
Annals of Surgery, 1976 The role of prostaglandins in endocrine diarrheagenic syndromes was evaluated by measuring peripheral concentration of immunoreactive PGE and PGF in patients with non-endocrine diarrhea as well as those with the Zollinger-Ellison (Z-E) syndrome, MCT, carcinoid tumors and the WDHA syndrome. In 21 normals, PGE and PGF levels averaged 272 +/- 18 and 119 +/
B M, Jaffe, S, Condon
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Identification and characterization of prostaglandin F2α 9-dehydrogenase from Rhodotorula kratochvilovae [PDF]
Applied Microbiology and BiotechnologyProstaglandin F2α (PGF2α) is one of the most important bioactive lipids in mammals. Developing a bioproduction system for PGF2α could enable low-cost production with minimal environmental impact.
Ukyo Shino +10 more
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Biomarkers and Mechanisms of Male Infertility: Evaluation of Antioxidant Enzymes and Arachidonic Acid Derivatives in Seminal Plasma from Fertile and Infertile Men [PDF]
AntioxidantsMale infertility accounts for approximately 50% of reproductive failures, yet its diagnosis and understanding of underlying mechanisms remain limited.
Kamil Rodak +4 more
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Improved de novo production of prostaglandin F2α from glucose with engineered Yarrowia lipolytica strains [PDF]
Communications BiologyProstaglandin F2α (PGF2α) is an important lipid mediator with diverse physiological activities, but its reliance on chemical synthesis presents challenges and limitations, driving the need for efficient microbial fermentation.
Guo-Wei He +8 more
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A heterogeneous mixture of F-series prostaglandins promotes sperm guidance in the Caenorhabditis elegans reproductive tract. [PDF]
PLoS Genetics, 2013 The mechanisms that guide motile sperm through the female reproductive tract to oocytes are not well understood. We have shown that Caenorhabditis elegans oocytes synthesize sperm guiding F-series prostaglandins from polyunsaturated fatty acid (PUFA ...
Hieu D Hoang +3 more
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Heliyon, 2023 Background: Most labor-related problems can be attributed to the uterine myometrium muscle, as this irritable tissue must suppress its irritability potential during pregnancy.
Farideh Zafari Zangeneh +1 more
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Cofactors in the biosynthesis of prostaglandins F and F .
Biochimica et biophysica acta, 1972 R E, Lee, W E, Lands
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Cytosolic Phospholipase A2α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation [PDF]
, 2013 Acknowledgments: We thank Dr. Robert Barkley and Charis Uhlson for mass spectrometry analysis. Funding: This work was supported by grants from the National Institutes of Health HL34303 (to C.C.L., R.C.M. and D.L.B), DK54741 (to J.V.B.), GM5322 (to D.L.W.)
Bonventre, Joseph V. +9 more
core +10 more sources