Assessment of Lipid Peroxidation in Alzheimer’s Disease Differential Diagnosis and Prognosis
Alzheimer’s disease (AD) and other dementias are becoming increasingly common in the older population, and the number of people affected is expected to increase in a few years.
Laura Ferré-González +3 more
doaj +1 more source
Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]
Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A. +6 more
core +1 more source
Preparation of Prostaglandin F from Prostaglandin E. Prostaglandins and Related Factors. 6. [PDF]
Reduction of prostaglandin E (PGE) with sodium borohydride yielded 2 compounds 1 of which is identical with PGF isolated from the prostate of sheep and the other of which had different physical and biological properties but the same elementary composition. The former was designated PGF1 and the latter PGF2.
Sune Bergström +5 more
openaire +1 more source
A Blend of F Prostaglandins Functions as an Attractive Sex Pheromone in Silver Carp
A series of laboratory experiments tested the hypothesis that the Silver Carp (Hypophthalmichthys molitrix), an invasive river carp from China, employs a prostaglandin F2α-derived sex pheromone that is attractive and species-specific.
Peter W. Sorensen +4 more
doaj +1 more source
Aspirin treatment of mice infected with Trypanosoma cruzi and implications for the pathogenesis of Chagas disease. [PDF]
Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate host response and disease progression.
Shankar Mukherjee +13 more
doaj +1 more source
Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes [PDF]
Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition.
Aardema +49 more
core +2 more sources
Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico +8 more
core +1 more source
Colocalization of prostaglandin F2α receptor FP and prostaglandin F synthase-I in the spinal cord [PDF]
Prostaglandin F(2alpha) is synthesized by prostaglandin F synthase, which exists in two types, prostaglandin F synthase I (PGFS I) and prostaglandin F synthase II (PGFS II). Prostaglandin F(2alpha) binds to its specific receptor, FP. Our previous immunohistochemical study showed the distinct localization of prostaglandin F synthases in rat spinal cord.
T. Suzuki-Yamamoto +3 more
openaire +3 more sources
Aldo-keto reductases 1B in adrenal cortex physiology
Aldose reductase proteins are cytosolic monomeric enzymes, belonging to the aldo-keto reductase (AKR) superfamily. They perform oxidoreduction of carbonyl groups from a wide variety of substrates such as aliphatic and aromatic aldehydes or ketones.
Emilie PASTEL +3 more
doaj +1 more source
Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P +11 more
core +1 more source

