Aspirin treatment of mice infected with Trypanosoma cruzi and implications for the pathogenesis of Chagas disease. [PDF]
PLoS ONE, 2011 Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate host response and disease progression.
Shankar Mukherjee +13 more
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Colocalization of prostaglandin F2α receptor FP and prostaglandin F synthase-I in the spinal cord [PDF]
Journal of Lipid Research, 2009 Prostaglandin F(2alpha) is synthesized by prostaglandin F synthase, which exists in two types, prostaglandin F synthase I (PGFS I) and prostaglandin F synthase II (PGFS II). Prostaglandin F(2alpha) binds to its specific receptor, FP. Our previous immunohistochemical study showed the distinct localization of prostaglandin F synthases in rat spinal cord.
T. Suzuki-Yamamoto +3 more
openaire +3 more sources
Aldo-keto reductases 1B in adrenal cortex physiology
Frontiers in Endocrinology, 2016 Aldose reductase proteins are cytosolic monomeric enzymes, belonging to the aldo-keto reductase (AKR) superfamily. They perform oxidoreduction of carbonyl groups from a wide variety of substrates such as aliphatic and aromatic aldehydes or ketones.
Emilie PASTEL +3 more
doaj +1 more source
Enzymic separatory determination of prostaglandin F and F.
Chemical and Pharmaceutical Bulletin, 1975 A simple and sensitive method is described for separatory determination of prostaglandin E and prostaglandin F. This method is based on three principles : (1) Prostaglandin E and prostaglandin F are oxidized by prostaglandin dehydrogenase, resulting reduced nicotinamide-adenine dinucleotide (NADH).
ITAMI, TAKAFUMI +3 more
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Modulation of Amnionic Adenylate Cyclase and cAMP Phosphodiesterase by Prostaglandins E(1) and F2α [PDF]
, 1994 The action of prostaglandins E1 and F2αon adenylate cyclas and cAMP phos-phodiesterase was assayed in cell membrane fractions of amnion obtained before and after labor from term physiological pregnancies.
TARABBIA C +6 more
core +1 more source
Effects of prostaglandins F alpha on dog thyroid cyclic AMP level and function. [PDF]
, 1982 Prostaglandins F1 alpha and F2 alpha, at high concentrations (greater than or equal to 28 microM) enhanced cyclic AMP accumulation in dog thyroid slices.
Dumont, Jacques Emile +4 more
core +1 more source
Prostanoid Signaling in Cancers: Expression and Regulation Patterns of Enzymes and Receptors
Biology, 2022 Cancer-associated disturbance of prostanoid signaling provides an aberrant accumulation of prostanoids. This signaling consists of 19 target genes, encoding metabolic enzymes and G-protein-coupled receptors, and prostanoids (prostacyclin, thromboxane ...
Pavel V. Ershov +4 more
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Trypanosoma cruzi infection and endothelin-1 cooperatively activate pathogenic inflammatory pathways in cardiomyocytes. [PDF]
PLoS Neglected Tropical Diseases, 2013 Trypanosoma cruzi, the causative agent of Chagas' disease, induces multiple responses in the heart, a critical organ of infection and pathology in the host.
Ricardo S Corral +4 more
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Prostaglandin F in the Fallopian Tube Secretion of the Ewe [PDF]
Australian Journal of Biological Sciences, 1978 Oviducal secretions were obtained from conscious unrestrained ewes throughout the oestrous cycle via indwelling cannulae and the content of prostaglandin F (pGF) was determined by radioimmunoassay. Levels of PGF of up to 230 ngjml were found in oviducal fluids obtained from ewes showing regular patterns of secretion and normal cyclical ovarian function
G M, Warnes, F, Amato, R F, Seamark
openaire +2 more sources
Molecules, 2018 Cyclooxygenase 2 (COX-2) is an inducible enzyme responsible for the conversion of arachidonic acid into the prostaglandins, PGG2 and PGH2. Expression of this enzyme increases in inflammation.
Michelle Y. Cortes-Salva +8 more
doaj +1 more source