Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Conserved deletion of two consecutive glycine residues in the 100K protein is a critical determinant of FAdV-11 pathogenicity. [PDF]
VirulenceWang B +15 more
europepmc +1 more source
Dynamics and origin of the late orogenic topography of the Betic domain (Spain)
, 2017 Competing between internal and external processes controls the evolution of continental surfaces at geological time scale. The topography and associated drainage network of the Betics are transient (summit surfaces, knickpoints) implying that the erosional response of the geomorphic system hasn’t counterbalanced the last stages of uplift yet ...
openaire +2 more sources
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Molecular signatures and biomarker development for limbic-predominant age-related TDP-43 encephalopathy (LATE). [PDF]
Acta NeuropatholWu L +4 more
europepmc +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
Crustal melting and late-orogenic evolution of the South Armorican Domain
, 2010 The late-orogenic evolution of the South Armorican Domain (West European Variscan Belt), 0is characterized by a gravitational collapse of the thickened crust in an extensional tectonic setting. In the entire domain, this stage is coeval with a generalized crustal melting of the middle to lower crust, and with the exhumation of the deep metamorphic ...
openaire +1 more source
Identification of Non-basic Matrix Domain Residues That Impact HTLV-1 Gag Membrane Targeting and Particle Release. [PDF]
J Mol BiolMeng S +8 more
europepmc +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source
From transporter to motor: Evolutionary and structural insights into the emergence of prestin's area-motor activity in mammals. [PDF]
Protein SciFuentes-Ugarte N +6 more
europepmc +1 more source