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Membrane budding is a key step in vesicular transport, multivesicular body biogenesis, and enveloped virus release. These events range from those that are primarily protein driven, such as the formation of coated vesicles, to those that are primarily lipid driven, such as microdomain-dependent biogenesis of multivesicular bodies. Other types of budding
J. H. Hurley +3 more
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Histological assessment of budding, depth of invasion, and grading in oral squamous cell carcinoma: Correlation with regional metastasis [PDF]
Background: Assessment of budding and grading of oral squamous cell carcinoma (OSCC) establishes the prerequisite for its management as the first step toward personalized management.
Mohammed Abidullah
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Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions. On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus-host interactions and associated disease.
Shuzo Urata, Juan Carlos de la Torre
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To Bud or Not to Bud: A Perspective on Molecular Simulations of Lipid Droplet Budding [PDF]
Valeria Zoni +6 more
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N-Terminally Myristoylated Feline Foamy Virus Gag Allows Env-Independent Budding of Sub-Viral Particles [PDF]
Foamy viruses (FVs) are distinct retroviruses classified as Spumaretrovirinae in contrast to the other retroviruses, the Orthoretrovirinae. As a unique feature of FVs, Gag is not sufficient for sub-viral particle (SVP) release. In primate and feline FVs (
Yong-Boum Kim, Martin Löchelt, Yang Liu
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Gemmata algarum, a Novel Planctomycete Isolated from an Algal Mat, Displays Antimicrobial Activity
Axenic cultures of two strains, JC673T and JC717, both belonging to the phylum Planctomycetota, were isolated from distinct geographical locations in India.
Gaurav Kumar +10 more
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To bud or not to bud: the RET perspective in CAKUT [PDF]
Congenital anomalies of the kidneys or lower urinary tract (CAKUT) encompass a spectrum of anomalies that result from aberrations in spatio-temporal regulation of genetic, epigenetic, environmental, and molecular signals at key stages of urinary tract development.
T Keefe, Davis +2 more
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Tumour budding in solid cancers. [PDF]
Tumour budding is an emerging prognostic biomarker in colorectal cancer (CRC) and other solid cancers. Tumour buds are usually defined as isolated single cancer cells or clusters of up to four cancer cells located at the invasive tumour front.
Nagtegaal, I.D. +9 more
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Importance of Viral Late Domains in Budding and Release of Enveloped RNA Viruses
Late assembly (L) domains are conserved sequences that are necessary for the late steps of viral replication, acting like cellular adaptors to engage the ESCRT membrane fission machinery that promote virion release.
Lisa Welker +2 more
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Biophysical Modeling of SARS-CoV-2 Assembly: Genome Condensation and Budding
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spurred unprecedented and concerted worldwide research to curtail and eradicate this pathogen.
Siyu Li, Roya Zandi
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