Late domain dependent E-cadherin recruitment into extracellular vesicles [PDF]
Frontiers in Cell and Developmental Biology, 2022 E-cadherin, a transmembrane protein involved in epithelial cell-cell adhesion and signaling, is found in exosomal fractions isolated from human body fluids.
Sebastian Bänfer +6 more
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Extracellular vesicle surface display of αPD‐L1 and αCD3 antibodies via engineered late domain‐based scaffold to activate T‐cell anti‐tumor immunity [PDF]
Journal of Extracellular VesiclesExtracellular vesicles (EVs) are emerging as promising carriers for the delivery of therapeutic biologics. Genetic engineering represents a robust strategy for loading proteins of interest into EVs.
Rui Chen +9 more
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Functional interchangeability of late domains, late domain cofactors and ubiquitin in viral budding. [PDF]
PLoS Pathogens, 2010 The membrane scission event that separates nascent enveloped virions from host cell membranes often requires the ESCRT pathway, which can be engaged through the action of peptide motifs, termed late (L-) domains, in viral proteins.
Maria Zhadina, Paul D Bieniasz
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The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles. [PDF]
PLoS Pathogens, 2016 Arenaviruses cause severe diseases in humans but establish asymptomatic, lifelong infections in rodent reservoirs. Persistently-infected rodents harbor high levels of defective interfering (DI) particles, which are thought to be important for ...
Christopher M Ziegler +9 more
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Binding site plasticity in viral PPxY Late domain recognition by the third WW domain of human NEDD4. [PDF]
Sci Rep, 2019 AbstractThe recognition of PPxY viral Late domains by the third WW domain of the HECT-E3 ubiquitin ligase NEDD4 (hNEDD4-WW3) is essential for the completion of the budding process of numerous enveloped viruses, including Ebola, Marburg, HTLV1 or Rabies. hNEDD4-WW3 has been validated as a promising target for the development of novel host-oriented broad
Iglesias-Bexiga M +7 more
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Autoregressive moving average modeling of late reverberation in the frequency domain [PDF]
2016 24th European Signal Processing Conference (EUSIPCO), 2016 In this paper, the late part of a room response is modeled in the frequency domain as a complex Gaussian random process. The autocovariance function (ACVF) and power spectral density (PSD) are theoretically defined from the exponential decay of the late reverberation power.
Gael Richard +2 more
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Pathogens, 2021 Fusarium and late blight (fungal diseases of cereals and potatoes) are among the main causes of crop loss worldwide. A key element of success in the fight against phytopathogens is the timely identification of infected plants and seeds.
Nikita V. Penkov +6 more
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On the Late-Time Instability of MOT Solution to the Time-Domain PMCHWT Equation
IEEE Antennas and Wireless Propagation LettersThis paper investigates the late-time instability of marching-on-in-time solution to the time-domain PMCHWT equation. The stability analysis identifies the static solenoidal nullspace of the time-domain electric field integral operator as the primary cause of instability. Furthermore, it reveals that the instability mechanisms of the time-domain PMCHWT
Francesco Andriulli +2 more
exaly +6 more sources
A PLPPV sequence in the p8 region of Gag provides late domain function for mouse mammary tumor virus [PDF]
Virology, 2019 David E Ott, Lori V Coren
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Virus Hijacks Host Proteins and Machinery for Assembly and Budding, with HIV-1 as an Example
Viruses, 2022 Viral assembly and budding are the final steps and key determinants of the virus life cycle and are regulated by virus–host interaction. Several viruses are known to use their late assembly (L) domains to hijack host machinery and cellular adaptors to be
Chih-Yen Lin +4 more
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