Results 11 to 20 of about 4,141,686 (289)

Domain-wall formation in late-time phase transitions [PDF]

Physical Review D, 1992
We examine domain wall formulation in late time phase transitions. We find that in the invisible axion domain wall phenomenon, thermal effects alone are insufficient to drive different parts of the disconnected vacuum manifold. This suggests that domain walls do not form unless either there is some supplemental (but perhaps not unreasonable) dynamics ...
, Kolb, , Wang
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The Interplay between ESCRT and Viral Factors in the Enveloped Virus Life Cycle

Viruses, 2021
Viruses are obligate parasites that rely on host cellular factors to replicate and spread. The endosomal sorting complexes required for transport (ESCRT) system, which is classically associated with sorting and downgrading surface proteins, is one of the
Bo Meng, Andrew M. L. Lever
doaj   +1 more source

Separation and Characterization of Late Endosomal Membrane Domains [PDF]

Journal of Biological Chemistry, 2002
Very little is known about the biophysical properties and the lipid or protein composition of membrane domains presumably present in endocytic and biosynthetic organelles. Here we analyzed the membrane composition of late endosomes by suborganellar fractionation in the absence of detergent.
Kobayashi, Toshihide, Beuchat Schaad, Marie-Hélène, Chevallier, Julien, Makino, Asami, Mayran, Nathalie, Escola, Jean-Michel, Lebrand, Cécile, Cosson, Pierre, Kobayashi, Tetsuyuki, Gruenberg, Jean   +9 more
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A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes

Life, 2023
Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo
Manuel Adrián Velázquez-Cervantes, Yazmín Rocío Benítez-Zeferino, Arturo Flores-Pliego, Addy Cecilia Helguera-Repetto, David Eduardo Meza-Sánchez, José Luis Maravillas-Montero, Guadalupe León-Reyes, Javier Mancilla-Ramírez, Jorge Francisco Cerna-Cortés, María Isabel Baeza-Ramírez, Moises León-Juaárez   +10 more
doaj   +1 more source

Identification of Retroviral Late Domains as Determinants of Particle Size [PDF]

Journal of Virology, 1999
ABSTRACT Retroviral Gag proteins, in the absence of any other viral products, induce budding and release of spherical, virus-like particles from the plasma membrane. Gag-produced particles, like those of authentic retrovirions, are not uniform in diameter but nevertheless fall within a fairly narrow distribution of sizes.
L, Garnier, L J, Parent, B, Rovinski, S X, Cao, J W, Wills   +4 more
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Structural basis for viral late-domain binding to Alix [PDF]

Nature Structural & Molecular Biology, 2007
The modular protein Alix is a central node in endosomal-lysosomal trafficking and the budding of human immunodeficiency virus (HIV)-1. The Gag p6 protein of HIV-1 contains a LYPx(n)LxxL motif that is required for Alix-mediated budding and binds a region of Alix spanning residues 360-702.
Sangho, Lee, Anjali, Joshi, Kunio, Nagashima, Eric O, Freed, James H, Hurley   +4 more
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Functional Replacement of a Retroviral Late Domain by Ubiquitin Fusion [PDF]

Traffic, 2008
Retroviral Gag polyprotein precursors are both necessary and sufficient for the assembly and release of virus‐like particles (VLPs) from infected cells. It is well established that small Gag‐encoded motifs, known as late domains, promote particle release by interacting with components of the cellular endosomal sorting and ubiquitination machinery. The
Anjali, Joshi, Utpal, Munshi, Sherimay D, Ablan, Kunio, Nagashima, Eric O, Freed   +4 more
openaire   +2 more sources

Importance of Viral Late Domains in Budding and Release of Enveloped RNA Viruses [PDF]

Viruses, 2021
Late assembly (L) domains are conserved sequences that are necessary for the late steps of viral replication, acting like cellular adaptors to engage the ESCRT membrane fission machinery that promote virion release. These short sequences, whose mutation or deletion produce the accumulation of immature virions at the plasma membrane, were firstly ...
Lisa Welker, Jean-Christophe Paillart, Serena Bernacchi   +2 more
openaire   +4 more sources

Perbandingan Metode Penyelesaian Permasalahan Optimasi Lintas Domain dengan Pendekatan Hyper-Heuristic Menggunakan Algoritma Reinforcement-Late Acceptance

Jurnal Teknologi Informasi dan Ilmu Komputer, 2021
Sebuah organisasi terkadang membutuhkan solusi untuk permasalahan optimasi lintas domain. Permasalahan optimasi lintas domain merupakan permasalahan yang memiliki karakteristik berbeda, misalnya antar domain optimasi penjadwalan, rute kendaraan, bin ...
Anang Firdaus, Ahmad Muklason, Vicha Azthanty Supoyo   +2 more
doaj   +1 more source

Arenavirus Budding: A Common Pathway with Mechanistic Differences

Viruses, 2013
The Arenaviridae is a diverse and growing family of viruses that includes several agents responsible for important human diseases. Despite the importance of this family for public health, particularly in Africa and South America, much of its biology ...
Svenja Wolff, Hideki Ebihara, Allison Groseth   +2 more
doaj   +1 more source