Denoising Directional Room Impulse Responses with Spatially Anisotropic Late Reverberation Tails
Directional room impulse responses (DRIR) measured with spherical microphone arrays (SMA) enable the reproduction of room reverberation effects on three-dimensional surround-sound systems (e.g., Higher-Order Ambisonics) through multichannel convolution ...
Pierre Massé +3 more
doaj +1 more source
Patterns of late‐life depressive symptoms and subsequent declines in cognitive domains [PDF]
BackgroundDepression frequently co‐occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late‐life depressive symptom patterns to subsequent domain‐specific cognitive changes.MethodsDepressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health Study participants prior to cognitive ...
J Cai, Gillis +5 more
openaire +2 more sources
Rabaptin5 is recruited to endosomes by Rab4a and Rabex5 to regulate endosome maturation [PDF]
Membrane trafficking between organelles is fundamental to the existence of eukaryotic cells. A multitude of proteins is involved in membrane trafficking, acting as building blocks for transport carriers, regulators of transport, and targeting and fusion ...
Kälin, Simone
core +1 more source
Hrs promotes ubiquitination and mediates endosomal trafficking of smoothened in Drosophila hedgehog signaling. [PDF]
In Hedgehog (Hh) signaling, the seven-transmembrane protein Smoothened (Smo) acts as a signal transducer that is regulated by phosphorylation, ubiquitination, and cell surface accumulation.
Junkai Fan +3 more
doaj +1 more source
Late Domain-Dependent Inhibition of Equine Infectious Anemia Virus Budding [PDF]
ABSTRACT The Gag proteins of a number of different retroviruses contain late or L domains that promote the release of virions from the plasma membrane. Three types of L domains have been identified to date: Pro-Thr-Ala-Pro (PTAP), Pro-Pro-X-Tyr, and Tyr-Pro-Asp-Leu. It has previously been demonstrated that overexpression of the N-terminal, E2-
Miranda, Shehu-Xhilaga +5 more
openaire +2 more sources
In vivo identification of multiple promoter domains of adenovirus EIIA‐late promoter. [PDF]
The transcriptional control elements of the Adenovirus (Ad) type 5 EIIA-late (L) promoter were analyzed in the context of the viral chromosome. Promoter mutants constructed in vitro [deletion and linker-scanning (LS)] were re-introduced into the non-essential EIII region of an Ad5 variant which lacked the EIA gene.
G, Bhat +4 more
openaire +2 more sources
Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function [PDF]
Cholesterol regulates plasma membrane (PM) association and functioning of syntaxin-4 and soluble N-ethylmaleimide-sensitive fusion protein 23 (SNAP23) in the secretory pathway.
Enrich Bastús, Carles +25 more
core +1 more source
Viral late domains are used by many viruses to recruit the cellular endosomal sorting complex required for transport (ESCRT) to mediate membrane scission during viral budding.
Christopher M Ziegler +12 more
doaj +1 more source
Functional domains of the 50S subunit mature late in the assembly process
AbstractDespite the identification of many factors that facilitate ribosome assembly, the molecular mechanisms by which they drive ribosome biogenesis are poorly understood. Here, we analyze the late stages of assembly of the 50S subunit using Bacillus subtilis cells depleted of RbgA, a highly conserved GTPase.
Jomaa, Ahmad +5 more
openaire +2 more sources
Lysines Close to the Rous Sarcoma Virus Late Domain Critical for Budding [PDF]
ABSTRACT The release of retroviruses from the plasma membrane requires host factors that are believed to be recruited to the site of budding by the late (L) domain of the virus-encoded Gag protein. The L domain of Rous sarcoma virus (RSV) has been shown to interact with a ubiquitin (Ub) ligase, and budding of this virus is dependent on Ub ...
Jared L, Spidel +6 more
openaire +2 more sources

