Results 41 to 50 of about 672,964 (288)

Denoising Directional Room Impulse Responses with Spatially Anisotropic Late Reverberation Tails

open access: yesApplied Sciences, 2020
Directional room impulse responses (DRIR) measured with spherical microphone arrays (SMA) enable the reproduction of room reverberation effects on three-dimensional surround-sound systems (e.g., Higher-Order Ambisonics) through multichannel convolution ...
Pierre Massé   +3 more
doaj   +1 more source

Patterns of late‐life depressive symptoms and subsequent declines in cognitive domains [PDF]

open access: yesInternational Journal of Geriatric Psychiatry, 2016
BackgroundDepression frequently co‐occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late‐life depressive symptom patterns to subsequent domain‐specific cognitive changes.MethodsDepressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health Study participants prior to cognitive ...
J Cai, Gillis   +5 more
openaire   +2 more sources

Rabaptin5 is recruited to endosomes by Rab4a and Rabex5 to regulate endosome maturation [PDF]

open access: yes, 2014
Membrane trafficking between organelles is fundamental to the existence of eukaryotic cells. A multitude of proteins is involved in membrane trafficking, acting as building blocks for transport carriers, regulators of transport, and targeting and fusion ...
Kälin, Simone
core   +1 more source

Hrs promotes ubiquitination and mediates endosomal trafficking of smoothened in Drosophila hedgehog signaling. [PDF]

open access: yesPLoS ONE, 2013
In Hedgehog (Hh) signaling, the seven-transmembrane protein Smoothened (Smo) acts as a signal transducer that is regulated by phosphorylation, ubiquitination, and cell surface accumulation.
Junkai Fan   +3 more
doaj   +1 more source

Late Domain-Dependent Inhibition of Equine Infectious Anemia Virus Budding [PDF]

open access: yesJournal of Virology, 2004
ABSTRACT The Gag proteins of a number of different retroviruses contain late or L domains that promote the release of virions from the plasma membrane. Three types of L domains have been identified to date: Pro-Thr-Ala-Pro (PTAP), Pro-Pro-X-Tyr, and Tyr-Pro-Asp-Leu. It has previously been demonstrated that overexpression of the N-terminal, E2-
Miranda, Shehu-Xhilaga   +5 more
openaire   +2 more sources

In vivo identification of multiple promoter domains of adenovirus EIIA‐late promoter. [PDF]

open access: yesThe EMBO Journal, 1987
The transcriptional control elements of the Adenovirus (Ad) type 5 EIIA-late (L) promoter were analyzed in the context of the viral chromosome. Promoter mutants constructed in vitro [deletion and linker-scanning (LS)] were re-introduced into the non-essential EIII region of an Ad5 variant which lacked the EIA gene.
G, Bhat   +4 more
openaire   +2 more sources

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function [PDF]

open access: yes, 2011
Cholesterol regulates plasma membrane (PM) association and functioning of syntaxin-4 and soluble N-ethylmaleimide-sensitive fusion protein 23 (SNAP23) in the secretory pathway.
Enrich Bastús, Carles   +25 more
core   +1 more source

NEDD4 family ubiquitin ligases associate with LCMV Z's PPXY domain and are required for virus budding, but not via direct ubiquitination of Z.

open access: yesPLoS Pathogens, 2019
Viral late domains are used by many viruses to recruit the cellular endosomal sorting complex required for transport (ESCRT) to mediate membrane scission during viral budding.
Christopher M Ziegler   +12 more
doaj   +1 more source

Functional domains of the 50S subunit mature late in the assembly process

open access: yesNucleic Acids Research, 2013
AbstractDespite the identification of many factors that facilitate ribosome assembly, the molecular mechanisms by which they drive ribosome biogenesis are poorly understood. Here, we analyze the late stages of assembly of the 50S subunit using Bacillus subtilis cells depleted of RbgA, a highly conserved GTPase.
Jomaa, Ahmad   +5 more
openaire   +2 more sources

Lysines Close to the Rous Sarcoma Virus Late Domain Critical for Budding [PDF]

open access: yesJournal of Virology, 2004
ABSTRACT The release of retroviruses from the plasma membrane requires host factors that are believed to be recruited to the site of budding by the late (L) domain of the virus-encoded Gag protein. The L domain of Rous sarcoma virus (RSV) has been shown to interact with a ubiquitin (Ub) ligase, and budding of this virus is dependent on Ub ...
Jared L, Spidel   +6 more
openaire   +2 more sources

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