Results 41 to 50 of about 4,141,686 (289)
Multimodal imaging reveals the spatiotemporal dynamics of recollection. [PDF]
, 2012 Functional MRI research suggests that different frontal and parietal cortical regions support strategic processes that are engaged at different stages of recollection, from pre-retrieval processing of a cue to post-retrieval maintenance and evaluation of
Henson, Richard N. +5 more
core +1 more source
Late-Replicating Domains Have Higher Divergence and Diversity in Drosophila melanogaster [PDF]
Molecular Biology and Evolution, 2011 Several reports from mammals indicate that an increase in the mutation rate in late-replicating regions may, in part, be responsible for the observed genomic heterogeneity in neutral substitution rates and levels of diversity, although the mechanisms for this remain poorly understood.
Claudia C, Weber +2 more
openaire +2 more sources
Hrs promotes ubiquitination and mediates endosomal trafficking of smoothened in Drosophila hedgehog signaling. [PDF]
PLoS ONE, 2013 In Hedgehog (Hh) signaling, the seven-transmembrane protein Smoothened (Smo) acts as a signal transducer that is regulated by phosphorylation, ubiquitination, and cell surface accumulation.
Junkai Fan +3 more
doaj +1 more source
Domain-domain movement and conformational heterogeneity of hRPA.
, 2023 (A) Variation in the average value of inter-domain distances between DBD-A and DBD-B (R70A−70B >) (Å) as a function of ϵinter presented with the error bars.
Arnab Bhattacherjee (476141) +1 more
core +1 more source
Functional domains of the 50S subunit mature late in the assembly process
Nucleic Acids Research, 2013 AbstractDespite the identification of many factors that facilitate ribosome assembly, the molecular mechanisms by which they drive ribosome biogenesis are poorly understood. Here, we analyze the late stages of assembly of the 50S subunit using Bacillus subtilis cells depleted of RbgA, a highly conserved GTPase.
Jomaa, Ahmad +5 more
openaire +2 more sources
A Bipartite Late-Budding Domain in Human Immunodeficiency Virus Type 1 [PDF]
Journal of Virology, 2003 ABSTRACT Human immunodeficiency virus type 1 (HIV-1) encodes a PTAP motif within the p6 domain of Gag that recruits Tsg101 and associated factors to facilitate virion budding. In this study, we use trans -complementation assays to demonstrate that the PTAP motif acts synergistically with additional p6 ...
Martin-Serrano, J, Bieniasz, P D
openaire +3 more sources
PLoS Pathogens, 2019 Viral late domains are used by many viruses to recruit the cellular endosomal sorting complex required for transport (ESCRT) to mediate membrane scission during viral budding.
Christopher M Ziegler +12 more
doaj +1 more source
Late Domain-Dependent Inhibition of Equine Infectious Anemia Virus Budding [PDF]
Journal of Virology, 2004 ABSTRACT The Gag proteins of a number of different retroviruses contain late or L domains that promote the release of virions from the plasma membrane. Three types of L domains have been identified to date: Pro-Thr-Ala-Pro (PTAP), Pro-Pro-X-Tyr, and Tyr-Pro-Asp-Leu. It has previously been demonstrated that overexpression of the N-terminal, E2-
Miranda, Shehu-Xhilaga +5 more
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mBio, 2016 Enveloped viruses commonly utilize late-domain motifs, sometimes cooperatively with ubiquitin, to hijack the endosomal sorting complex required for transport (ESCRT) machinery for budding at the plasma membrane. However, the mechanisms underlying budding
Rina Barouch-Bentov +11 more
doaj +1 more source
In vivo identification of multiple promoter domains of adenovirus EIIA‐late promoter. [PDF]
The EMBO Journal, 1987 The transcriptional control elements of the Adenovirus (Ad) type 5 EIIA-late (L) promoter were analyzed in the context of the viral chromosome. Promoter mutants constructed in vitro [deletion and linker-scanning (LS)] were re-introduced into the non-essential EIII region of an Ad5 variant which lacked the EIA gene.
G, Bhat +4 more
openaire +2 more sources