Results 51 to 60 of about 4,141,686 (289)
Characterization of early and late transition states of the folding pathway of a
Protein Science, 2022 AbstractAlbeit SH2 domains are abundant protein–protein interaction modules with fundamental roles in the regulation of several physiological and molecular pathways in the cell, the available information about the determinants of their thermodynamic stability and folding properties are still very limited.
Angelo Toto +7 more
openaire +3 more sources
Supporting Variability with Late Semantic Adaptations of Domain-Specific Modeling Languages [PDF]
, 2010 International audienceMeta-object protocols are used to open up the implementations of object-oriented general-purpose languages to support semantic variability.
Dinkelaker, Tom +2 more
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho +6 more
wiley +1 more source
Refined study of the interaction between HIV-1 p6 late domain and ALIX
Retrovirology, 2008 The interaction between the HIV-1 p6 late budding domain and ALIX, a class E vacuolar protein sorting factor, was explored by using the yeast two-hybrid approach. We refined the ALIX binding site of p6 as being the leucine triplet repeat sequence (Lxx)4 (
Gerlier Denis +4 more
doaj +1 more source
Role of SNX16 in the Dynamics of Tubulo-Cisternal Membrane Domains of Late Endosomes
PLoS ONE, 2011 In this paper, we report that the PX domain-containing protein SNX16, a member of the sorting nexin family, is associated with late endosome membranes. We find that SNX16 is selectively enriched on tubulo-cisternal elements of this membrane system, whose highly dynamic properties and formation depend on intact microtubules.
Brankatschk, Ben +3 more
openaire +10 more sources
Lysines Close to the Rous Sarcoma Virus Late Domain Critical for Budding [PDF]
Journal of Virology, 2004 ABSTRACT The release of retroviruses from the plasma membrane requires host factors that are believed to be recruited to the site of budding by the late (L) domain of the virus-encoded Gag protein. The L domain of Rous sarcoma virus (RSV) has been shown to interact with a ubiquitin (Ub) ligase, and budding of this virus is dependent on Ub ...
Jared L, Spidel +6 more
openaire +2 more sources
Faster 3D finite element time domain : Floquet absorbing boundary condition modelling using recursive convolution and vector fitting [PDF]
, 2009 A recursive convolution (RC) based on the vector fitting (VF) method and triangular temporal basis functions is employed to compute the Floquet absorbing boundary condition (FABC) formulation in the vector 3D finite element time-domain (FETD) modelling ...
Cai, Yong, Mias, Christos
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
Rivista Italiana di Paleontologia e Stratigrafia, 2007 The Trucco Formation and the Nummulitic Limestone (Dauphinois Domain, Maritime Alps) are characterized by abundant larger foraminifera, specifically nummulitids, orthophragminids and encrusting foraminifera. In the Maritime Alps, previous studies suggest
DARIO VARRONE, DANIELLE DECROUEZ
doaj +1 more source
Patterns of late‐life depressive symptoms and subsequent declines in cognitive domains [PDF]
International Journal of Geriatric Psychiatry, 2016 BackgroundDepression frequently co‐occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late‐life depressive symptom patterns to subsequent domain‐specific cognitive changes.MethodsDepressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health Study participants prior to cognitive ...
J Cai, Gillis +5 more
openaire +2 more sources