Results 51 to 60 of about 672,964 (288)
mBio, 2016 Enveloped viruses commonly utilize late-domain motifs, sometimes cooperatively with ubiquitin, to hijack the endosomal sorting complex required for transport (ESCRT) machinery for budding at the plasma membrane. However, the mechanisms underlying budding
Rina Barouch-Bentov +11 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei +17 more
wiley +1 more source
Late-Replicating Domains Have Higher Divergence and Diversity in Drosophila melanogaster [PDF]
Molecular Biology and Evolution, 2011 Several reports from mammals indicate that an increase in the mutation rate in late-replicating regions may, in part, be responsible for the observed genomic heterogeneity in neutral substitution rates and levels of diversity, although the mechanisms for this remain poorly understood.
Claudia C, Weber +2 more
openaire +2 more sources
Characterization of early and late transition states of the folding pathway of a
Protein Science, 2022 AbstractAlbeit SH2 domains are abundant protein–protein interaction modules with fundamental roles in the regulation of several physiological and molecular pathways in the cell, the available information about the determinants of their thermodynamic stability and folding properties are still very limited.
Angelo Toto +7 more
openaire +3 more sources
Supporting Variability with Late Semantic Adaptations of Domain-Specific Modeling Languages [PDF]
, 2010 International audienceMeta-object protocols are used to open up the implementations of object-oriented general-purpose languages to support semantic variability.
Dinkelaker, Tom +2 more
core
Role of SNX16 in the Dynamics of Tubulo-Cisternal Membrane Domains of Late Endosomes
PLoS ONE, 2011 In this paper, we report that the PX domain-containing protein SNX16, a member of the sorting nexin family, is associated with late endosome membranes. We find that SNX16 is selectively enriched on tubulo-cisternal elements of this membrane system, whose highly dynamic properties and formation depend on intact microtubules.
Brankatschk, Ben +3 more
openaire +10 more sources
Functional characterization of the putative hepatitis B virus core protein late domain using retrovirus chimeras. [PDF]
PLoS One, 2013 The hepatitis B virus (HBV) Core protein encodes a late (L)-domain like motif (129PPAYRPPNAP(138)) that has been purported to serve as a docking site for recruitment of host factors such as Nedd4 that can mediate viral particle release from infected ...
Garcia ML +3 more
europepmc +2 more sources
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Rivista Italiana di Paleontologia e Stratigrafia, 2007 The Trucco Formation and the Nummulitic Limestone (Dauphinois Domain, Maritime Alps) are characterized by abundant larger foraminifera, specifically nummulitids, orthophragminids and encrusting foraminifera. In the Maritime Alps, previous studies suggest
DARIO VARRONE, DANIELLE DECROUEZ
doaj +1 more source
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source