Results 11 to 20 of about 160,204 (302)
N-Terminally Myristoylated Feline Foamy Virus Gag Allows Env-Independent Budding of Sub-Viral Particles [PDF]
Foamy viruses (FVs) are distinct retroviruses classified as Spumaretrovirinae in contrast to the other retroviruses, the Orthoretrovirinae. As a unique feature of FVs, Gag is not sufficient for sub-viral particle (SVP) release. In primate and feline FVs (
Yong-Boum Kim, Martin Löchelt, Yang Liu
doaj +2 more sources
PDGFRα<sup>+</sup>/Integrin α2<sup>+</sup> Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano-Metabolic Symbiosis: E-Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer. [PDF]
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Liu Y +17 more
europepmc +2 more sources
Tumour budding in solid cancers. [PDF]
Tumour budding is an emerging prognostic biomarker in colorectal cancer (CRC) and other solid cancers. Tumour buds are usually defined as isolated single cancer cells or clusters of up to four cancer cells located at the invasive tumour front.
Nagtegaal, I.D. +9 more
core +1 more source
The Hippo signaling pathway has been shown to be involved in regulating cellular identity, cell/tissue size maintenance and mechanotransduction. The Hippo pathway consists of a kinase cascade which determines the nucleo-cytoplasmic localization of YAP in
Manu Unni +6 more
doaj +1 more source
We propose a new decision tree model, named the budding tree, where a node can be both a leaf and an internal decision node. Each bud node starts as a leaf node, can then grow children, but then later on, if necessary, its children can be pruned. This contrasts with traditional tree construction algorithms that only grows the tree during the training ...
Ozan Irsoy +2 more
openaire +1 more source
Alterations of membrane curvature during influenza virus budding [PDF]
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
core +1 more source
Roles of the three L-domains in β-retrovirus budding [PDF]
Retroviral Gag protein plays a critical role during the late stage of virus budding and possesses a so-called L-domain containing PT/SAP, PPxY, YxxL or FPIV motifs that are critical for efficient budding.
Jiro Yasuda +4 more
core +1 more source
Innovation in Propagation of Fruit, Vegetable and Ornamental Plants
There are two primary forms of plant propagation: sexual and asexual. In nature, propagation of plants most often involves sexual reproduction, and this form is still used in several species.
Sergio Ruffo Roberto +1 more
doaj +1 more source
How to halve ploidy : lessons from budding yeast meiosis [PDF]
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Kerr, Gary W. +3 more
core +1 more source
Virus Hijacks Host Proteins and Machinery for Assembly and Budding, with HIV-1 as an Example
Viral assembly and budding are the final steps and key determinants of the virus life cycle and are regulated by virus–host interaction. Several viruses are known to use their late assembly (L) domains to hijack host machinery and cellular adaptors to be
Chih-Yen Lin +4 more
doaj +1 more source

