Results 131 to 140 of about 1,301,845 (266)

Effect of Myofascial Therapy After Surgery and Radiotherapy in Breast Cancer Treatment

open access: yesFysioterapeuten
Purpose: Many women experience physical late effects after surgery and radiotherapy as part of breast cancer treatment and need physiotherapy. Myofascial therapy is a commonly used treatment for these late effects, though scientific evidence is limited ...
Cecilie Erga   +2 more
doaj  

Early and Late Effects of Difluorodeoxycytidine on Murine Cell Radiosensitivity <i>In Vivo</i>. [PDF]

open access: yesIn Vivo
Cruz-Vallejo V   +4 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Self-reported late effects and chronic fatigue, information needs and follow-up in long-term survivors of Hodgkin lymphoma-a cross-sectional study. [PDF]

open access: yesSupport Care Cancer
Willumsen LH   +9 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Identifying clustering in patterns of late effects among survivors of adolescent and young adult Hodgkin lymphoma. [PDF]

open access: yesJNCI Cancer Spectr
Parker K   +14 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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