Results 51 to 60 of about 1,710,497 (241)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Late Quaternary hydroclimate and vegetation changes in an upland lake in southeastern Amazonia
Anais da Academia Brasileira de Ciências, 2023 An integrated approach considering facies, isotopic, and palynological analyses of lake sediments from the Serra Norte de Carajás, southeastern Amazonia, is presented in this work to refine paleoclimate and paleohydrological changes based on upland lake ...
EDILSON F. DA SILVA +9 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Holocene Moisture Variations in Western Arid Central Asia Inferred From Loess Records From NE Iran
Geochemistry, Geophysics, Geosystems, 2020 Holocene variations in precipitation in central and eastern arid central Asia (ACA) have been widely investigated, but the pattern in western ACA remains unclear. We present records of the stable carbon isotope composition of bulk organic matter (δ13Corg)
Qiang Wang +9 more
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Holocene Monsoonal Variations Over Southern India: Looking Into Its Antecedents
Frontiers in Earth Science, 2022 A proper understanding of the paleoclimatic variability in the Southern Peninsular India demands a high-resolution paleoclimate reconstruction record. Hence, in this paper, we compiled all the available paleoclimate records from various locations across ...
M. R. Resmi +2 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Anais da Academia Brasileira de Ciências, 2022 Diatom assemblages and coastal sedimentary facies succession in the deltaic plain of the Colorado River (Argentina) were studied in order to reconstruct the environment conditions in response to Holocene eustatic sea-level changes and delta progradation.
ROCÍO FAYÓ +2 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Late Pleistocene to Holocene environmental changes from δ13C determinations in soils at Teotihuacan, Mexico [PDF]
Geofísica Internacional, 2006 Stable carbon isotopic signature (δ13C) of soil organic matter (SOM) is used as a high-spatial resolution tool to infer environmental changes during late Pleistocene to Present in the Teotihuacan valley, Mexico.
E. Vallejo Gómez +6 more
doaj
Frontiers in Ecology and Evolution, 2022 As the recent permafrost thawing of northern Asia proceeds due to anthropogenic climate change, precise and detailed palaeoecological records from past warm periods are essential to anticipate the extent of future permafrost variations.
Wenjia Li +8 more
doaj +1 more source