Results 61 to 70 of about 1,710,497 (241)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Holocene Ecohydrological Variability on the East Coast of Kamchatka

open access: yesFrontiers in Earth Science, 2019
The Late Glacial and Holocene climate of the western North Pacific is less studied than that of the eastern North Pacific. While it is well known that strong east-west gradients in the tropical Pacific Ocean influence terrestrial climate, we seek to ...
Jonathan Nichols   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Decompacting a Late Holocene sea-level record from Loch Laxford, northwest Scotland. [PDF]

open access: yes, 2013
This thesis assesses the degree to which sediment compression affects a Late Holocene sea-level reconstruction from Loch Laxford, northwest Scotland. The reconstruction is based on analysis of a short sediment core (~0.7 m) that records a progressive ...
CULLEN, BENJAMIN,JOHN
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Tracing giants through time: stable isotope insights into the historical ecology of North Atlantic sperm whales (Physeter macrocephalus)

open access: yesFrontiers in Environmental Archaeology
IntroductionSperm whales (Physeter macrocephalus) are deep-diving apex predators whose offshore ecology limits direct observation. Stable isotope analysis is widely used to infer cetacean diet and habitat use, but its application to archaeological whale ...
Youri van den Hurk   +5 more
doaj   +1 more source

From the Allerød to the mid-Holocene: Palynological evidence from the south basin of the Caspian Sea [PDF]

open access: yes, 2013
This article has been made available through the Brunel Open Access Publishing Fund. Copyright @ The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which
López-Merino, L   +13 more
core   +1 more source

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