Results 81 to 90 of about 1,282,772 (281)

Structure of a Dengue Virus Envelope Protein Late-Stage Fusion Intermediate [PDF]

Journal of Virology, 2013
ABSTRACT The final stages of dengue virus fusion are thought to occur when the membrane-proximal stem drives the transmembrane anchor of the viral envelope protein (E) toward the fusion loop, buried in the target cell membrane. Crystal structures of E have lacked this essential stem region.
Klein, Daryl E., Choi, Jason L., Harrison, Stephen C.   +2 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses.

PLoS Pathogens, 2020
The induction of an interferon-mediated response is the first line of defense against pathogens such as viruses. Yet, the dynamics and extent of interferon alpha (IFNα)-induced antiviral genes vary remarkably and comprise three expression clusters: early,
Katharina Robichon, Tim Maiwald, Marcel Schilling, Annette Schneider, Joschka Willemsen, Florian Salopiata, Melissa Teusel, Clemens Kreutz, Christian Ehlting, Jun Huang, Sajib Chakraborty, Xiaoyun Huang, Georg Damm, Daniel Seehofer, Philipp A Lang, Johannes G Bode, Marco Binder, Ralf Bartenschlager, Jens Timmer, Ursula Klingmüller   +19 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Magnetism, rotation and accretion in Herbig Ae-Be stars

, 2007
Studies of stellar magnetism at the pre-main sequence phase can provide important new insights into the detailed physics of the late stages of star formation, and into the observed properties of main sequence stars.
Blondel, Bouret, C. Catala, C. Folsom, Catala, Catala, Catala, Catala, Catala, Collier Cameron, E. Alecian, G.A. Wade, Hubrig, J. Grunhut, J.-C. Bouret, J.-F. Donati, J.D. Landstreet, Landi, Lignières, Morel, Natta, P. Petit, S. Bagnulo, Stepień, Stepień, T. Boehm, Thé, Wade   +27 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

MYRACRODRUON URUNDEUVA FR ALL. (AROEIRA TREE) POPULATION DYNAMICS, DIAMETER GROWTH RATE AND ITS POTENTIAL FOR SUSTAINABLE MANAGEMENT IN SUCCESSIONAL TROPICAL DRY FORESTS OF BRAZIL

Revista Árvore, 2018
Myracrodruon urundeuva, better known in Brazil as “Aroeira”, is an arboreal species highly used for its commercial and pharmacological value. Despite the high commercial value in the timber market, this species lacks studies analyzing the recovery time ...
Sofia Calvo Rodriguez, Julio Calvo Alvarado, Mario Marcos do Espírito-Santo, Yule Roberta Ferreira Nunes   +3 more
doaj   +1 more source

Darboux transformations for quasi-exactly solvable Hamiltonians

, 2002
We construct new quasi-exactly solvable one-dimensional potentials through Darboux transformations. Three directions are investigated: Reducible and two types of irreducible second-order transformations.
Andrianov A. A., B. VAN DEN BOSSCHE, Bagrov V. G., BORIS F. SAMSONOV, Darboux G., Krein M. G., N. DEBERGH, Schrödinger E., Sparenberg J.-M., Sukumar C. V.   +9 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source