Results 111 to 120 of about 4,945,424 (246)

Institutionalized Hypocrisy

Oñati Socio-Legal Series
This paper draws on analysis by social historians ranging from the late Middle Ages and Renaissance in France to recent administrative history in Poland to illustrate basic contradictions in Western thought about sexuality. These have resulted over time
Jacek Kurczewski
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Krzysztof Ożóg, The Role of Poland in the Intellectual Development of Europe in the Middle Ages [Krakow Historical Monographs, vol. I], Societas Vistulana, Kraków 2009, ss. 231. [PDF]

, 2012
Krzysztof Ożóg, The Role of Poland in the Intellectual Development of Europe in the Middle Ages [Krakow Historical Monographs, vol.
Ratajczak, Krzysztof
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Interpreting Transformations of People and Landscapes in Late Antiquity and the Early Middle Ages. Archaeological Approaches and Issues

, 2018
In this volume of papers, deriving from two conferences held in Rome and Leicester in 2016, nineteen leading European archaeologists discuss and interpret the complex evolution of landscapes – both urban and rural – across Late Antiquity and the Early ...
Seaman, Andy, Brogiolo, Gian Pietro, Meneghini, Roberto, Vigil-Escalera Guirado, Alfonso, Chavarría Arnau, Alexandra, Raynaud, Claude, Esmonde Cleary, Simon, Collins, Rob, Diarte-Blasco, Pilar, Heeren, Stijn, Arce, Javier, Christie, Neil, Goffredo, Roberto, Ariño, Enrique, Tompkins, Abigail E. I., Olmo Enciso, Lauro, Volpe, Giuliano, Rippon, Stephen, White, Roger   +18 more
core  

Staging medievalisms : touching the Middle Ages through contemporary performance [PDF]

, 2013
textStaging Medievalisms analyzes how twentieth- and twenty-first century performance constructs the Middle Ages. This work is in conversation with medievalism, the academic field concerned with the diverse ways post-medieval societies have re-imagined ...
Gutierrez, Christina Lynn
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source