Results 91 to 100 of about 4,945,424 (246)

Marks on late medieval barrels from the southern Baltic coast

open access: yesArcheologické Rozhledy
In late medieval trade, barrels were the most popular containers for transporting various commodities. They were often marked with various symbols, the meaning of which is difficult to interpret.
Maciej Miścicki
doaj   +1 more source

Zero Waste. Some Remarks About Copper Alloy Bowls Recycling in the High and Late Middle Ages

open access: yesFasciculi Archaeologiae Historicae, 2019
The article presents the results of interpretation of a parts of a copper alloy bowls from the 10th-13th centuries. The vessels might have been originally used for liturgical ceremonies.
Andrzej Janowski
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Mapping Global Middle Ages, Toward a Global Middle Ages

open access: yes, 2019
In Order to understand what a "global Middle Ages" might be, we need to define "global" in and in relation to the "Middle Ages." To do so, I turn to medieval (Christian) maps.
Asa Simon Mittman, Bryan C. Keene
core   +1 more source

Time Management at School from the Late Middle Ages to the Industrial Age. A Few Cases in Point

open access: yes, 2020
The aim of this essay is to account for the progressive development of strategies forvparcelling and organizing time at school, that is, the distribution and realization of tasks on a shared timeline.
Pruneri, Fabio
core   +1 more source

The saddle of the late medieval steppe nomads

open access: yesFasciculi Archaeologiae Historicae, 2008
...
Witold Świętosławski
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

From Vicus to Village: Italian Landscapes, AD 400-1000 [PDF]

open access: yes, 2004
Overview of the develoment of rural settlement in Italy from Late Antiquity to the early Middle Ages. The various topics discussed include the transformation of late antique settlement, infrastructures of exchange, the role of the Church, the appearance ...
ARTHUR, Paul Raymond
core  

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