Results 71 to 80 of about 4,945,424 (246)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Introduction: The Middle Ages

, 2020
Episcopal sees were established from the early Middle Ages on, at first in Denmark from the middle of the tenth century, and a little bit later in Norway and Sweden.
Bertil Nilsson, Helle Vogt, Nilsson, Bertil,, Nilsson, Bertil, Vogt, Helle   +4 more
core   +1 more source

Gantelet : fragment d'armure datant du XVIe siècle et provenant du château d'Inowlódz, dép. de Piotrków (Pologne centrale)

Fasciculi Archaeologiae Historicae, 1988
...
Jerzy Augustyniak
doaj  

A Muslim Holy Man to Convert Christians in a Transottoman Setting: Approaches to Sarı Saltuk from the Late Middle Ages to the Present

Entangled Religions - Interdisciplinary Journal for the Study of Religious Contact and Transfer, 2019
Interpretations of texts on Sarı Saltuk may serve as a central example of the entanglement of Muslim and Christian contexts in (south-)eastern Europe and the Near East.
Stefan Rohdewald
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Dwór na kopcu w Lipinkach, pow. wschowski. Siedziba rycerska na pograniczu Śląska i Wielkopolski

Przegląd Archeologiczny
The article presents the results of archaeological and historical research on a small knight's residence from the village of Lipinki located in the eastern part of the former Duchy of Głogów.
Dagmara Adamska, Dominik Nowakowski
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Historiography and Identity V: Thee Emergence of New Peoples and Polities in Europe, 1000–1300

, 2022
The six-volume sub-series Historiography and Identity unites a wide variety of case studies from Antiquity to the late Middle Ages, from the Latin West to the emerging polities in Northern and Eastern Europe, and adding a Eurasian perspective that ...
Borri, Francesco, Wieser, Veronika, Walter Pohl, Veronika Wieser, Pohl, Walter, Francesco Borri   +4 more
core  

Nowa Nieszawa (Dybów) in the late Middle Ages according to new research. The town on the border of countries, cultures and nations

Klio, 2018
Nowa Nieszawa, lokowana nad Wisłą na pograniczu polsko-krzyżackim po 1423 roku, jawi się jako prężnie rozwijający się pod względem gospodarczym i politycznym ośrodek miejski.
Michalina Duda, Sławomir Jóźwiak
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source