Results 71 to 80 of about 4,239,875 (240)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Libraries and manuscripts in the general legislation of Friars Minor in late Middle Ages
The article presents the subject of studio and library legislation in the Order of Friars Minor in the late-medieval period.
Wiesław Franciszek Murawiec
doaj +1 more source
National Security Strategy of the Republic of Poland, 2014 [PDF]
"The strategy refers in a comprehensive manner to issues of national security and indicates optimal uses of all means that the state has at its disposal in the sphere of defence, protection, society and economy for security purposes.
Ministry of National Defence of Poland
core
The Individual and Society in the Middle Ages
Originally published in 1966. The Individual and Society in the Middle Ages, based on three guest lectures given at Johns Hopkins University in 1965, explores the place of the individual in medieval European society.
Ullmann, Walter
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
The 1987 conference in Århus, Denmark on ESF Workshop on the reconstruction of wooden buildings from the prehistoric and early historic period has been important to EXARC as we have acquired, and are gradually publishing, the manuscripts of the ...
Roeland P Paardekooper
doaj
Interpretations of texts on Sarı Saltuk may serve as a central example of the entanglement of Muslim and Christian contexts in (south-)eastern Europe and the Near East.
Stefan Rohdewald
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Book Review: Sailing into the Past: Learning from Replica Ships by Jenny Bennett (ed)
There must be hundreds of wooden ship replicas across the world, not only the ‘Viking ships’ in Scandinavia, but – as the book Sailing into the past shows, there are many medieval and more recent ones.
Roeland P Paardekooper
doaj

