Results 111 to 120 of about 119,179,614 (214)
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He +4 more
wiley +1 more source
Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges
Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu +7 more
wiley +1 more source
Latent Autoimmune Diabetes of Adults Due to Positive Zinc Transporter 8 Antibody
This case series reports 3 patients who were diagnosed with type 2 diabetes mellitus (T2DM), treated with oral antidiabetic medications, referred to our endocrinology clinic due to poor glycemic control, and were diagnosed with latent autoimmune diabetes
Jacob Maniattu +3 more
doaj +1 more source
Abstract Background Clinical services for adults with early‐onset type 2 diabetes (EOT2D) are in urgent need of improvement. Methods We evaluated a multi‐disciplinary clinic for individuals with EOT2D at high risk (HbA1c >9%/triglyceride >20 mmol/L), providing 2–3 flexibly arranged consultations per individual between March 2024 and September 2025 ...
Jonathan Goldney +14 more
wiley +1 more source
ABSTRACT Aims To examine the association between branched‐chain α‐keto acids (BCKAs) and pancreatic steatosis in patients with type 2 diabetes (T2DM). Methods This cross‐sectional study was conducted from January 2023 to March 2025. Upper abdominal computerized tomography was performed, pancreatic volume (PV), PV index (PVI), CT attenuation of pancreas
Jie Gao +9 more
wiley +1 more source
This study evaluated serum miRNAs as biomarkers in adult patients with SPIDDM. Serum miRNAs were measured at the time of SPIDDM (probable) diagnosis, and miR‐150‐5p was inversely associated with CPI at the last outpatient visit, suggesting its potential utility for predicting subsequent insulin secretory decline.
Hideyuki Okuma +4 more
wiley +1 more source
Circulating TGF‐β1 Increases During Vaginal Progesterone Therapy in Women With a Short Cervix
Progesterone treatment was associated with increased plasma TGF‐β1 concentrations in pregnant women at risk of spontaneous preterm birth. These findings suggest that progesterone may enhance immunoregulatory pathways relevant to pregnancy maintenance, although the underlying mechanism remains to be established.
Zdeněk Laštůvka +7 more
wiley +1 more source
Clinical Approach to Latent Autoimmune Diabetes in Adults: State of the Art and Future Perspectives
Latent autoimmune diabetes in adults (LADA) is the most common form of type 1 diabetes (T1D) that appears in adulthood. Initially, its clinical presentation resembles type 2 diabetes (T2D).
İlhan Satman
doaj +1 more source
A study of Latent Autoimmune Diabetes in Adults and ketosis prone type 2 diabetes mellitus
Latent Autoimmune Diabetes in Adults (LADA) is an ill-defined autoimmune disorder separated from typical type 1 diabetes (DM-1), because of features suggestive of type 2 diabetes (DM-2). To better understand LADA, we compared it with ketosis prone type 2
Djekic, Kristina
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