Investigating trajectories of social recovery in individuals with first-episode psychosis: A latent class growth analysis [PDF]
BackgroundSocial disability is a hallmark of severe mental illness yet individual differences and factors predicting outcome are largely unknown.AimTo explore trajectories and predictors of social recovery following a first episode of psychosis (FEP).MethodA sample of 764 individuals with FEP were ...
Hodgekins, Joanne +12 more
openaire +7 more sources
Victimization Profiles, Non-Suicidal Self-Injury, Suicide Attempt, and Post-Traumatic Stress Disorder Symptomology: Application of Latent Class Analysis. [PDF]
Few studies have incorporated multiple dimensions of victimization or examined whether victimization profiles differ by gender. Consequently, the present study sought to extend prior research by using latent class analysis (LCA) to identify naturally ...
Dhingra, Katie +6 more
core +1 more source
Executive function is the mental ability to modulate behavior or thinking to accomplish a task. This is developmentally important for children’s academic achievements and ability to adjust to school.
Eun-Kyoung Goh, Hyo-Jeong Jeon
doaj +1 more source
Background The prevalence of hypertension is high (25.2% in 2012) and there were a large number of patients with hypertension (more than 200 million) in China.
Lei Duan +3 more
doaj +1 more source
Model Fit and Comparison in Finite Mixture Models: A Review and a Novel Approach
One of the greatest challenges in the application of finite mixture models is model comparison. A variety of statistical fit indices exist, including information criteria, approximate likelihood ratio tests, and resampling techniques; however, none of ...
Kevin J. Grimm +2 more
doaj +1 more source
Latent class growth analysis procedure and model fit.
Latent class growth analysis procedure and model fit.
Jaap van Weeghel (532144) +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Using latent class growth analysis to form trajectories of premorbid adjustment in schizophrenia. [PDF]
Premorbid adjustment varies widely among individuals with schizophrenia and has been shown to bear significantly on prodrome and onset characteristics, and on cognition, symptoms, and functioning after onset. The current analysis focused on the Premorbid Adjustment Scale, a retrospective measure assessing social and academic function at several time ...
Veronica T, Cole +3 more
openaire +2 more sources
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source

